Increased FLYWCH1 Expression is Negatively Correlated with Wnt/β-catenin Target Gene Expression in Acute Myeloid Leukemia Cells

by Amany Almars, Panagiota S. Chondrou, Emenike K. Onyido, Sheema Almozyan, Claire Seedhouse, Roya Babaei-Jadidi, Abdolrahman S. Nateri
Published 2019-06-01

Predicting effective pro-apoptotic anti-leukaemic drug combinations using co-operative dynamic BH3 profiling.

by Martin Grundy, Claire Seedhouse, Thomas Jones, Liban Elmi, Michael Hall, Adam Graham, Nigel Russell, Monica Pallis
Published 2018-01-01

Ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase inhibition is synthetically lethal in XRCC1 deficient ovarian cancer cells.

by Rebeka Sultana, Tarek Abdel-Fatah, Christina Perry, Paul Moseley, Nada Albarakti, Vivek Mohan, Claire Seedhouse, Stephen Chan, Srinivasan Madhusudan
Published 2013-01-01