FOXP3 and Tip60 Structural Interactions Relevant to IPEX Development Lead to Potential Therapeutics to Increase FOXP3 Dependent Suppressor T Cell Functions

by Payal Grover, Peeyush N. Goel, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo, Mark I. Greene
Published 2021-02-01

Plasmodium chabaudi AS Infection Induces CD4+ Th1 Cells and Foxp3+T-bet+ Regulatory T Cells That Express CXCR3 and Migrate to CXCR3 Ligands

by Floriana Berretta, Floriana Berretta, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo, Mary M. Stevenson, Mary M. Stevenson
Published 2019-03-01

Pleiotropic Effects of IL-33 on CD4+ T Cell Differentiation and Effector Functions

by Fernando Alvarez, Fernando Alvarez, Fernando Alvarez, Jörg H. Fritz, Jörg H. Fritz, Jörg H. Fritz, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo
Published 2019-03-01

Foxp3 Post-translational Modifications and Treg Suppressive Activity

by Guoping Deng, Xiaomin Song, Shigeyoshi Fujimoto, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo, Yasuhiro Nagai, Mark I. Greene
Published 2019-10-01

Signaling Through gp130 Compromises Suppressive Function in Human FOXP3+ Regulatory T Cells

by Khalid Bin Dhuban, Khalid Bin Dhuban, Khalid Bin Dhuban, Sabrina Bartolucci, Sabrina Bartolucci, Sabrina Bartolucci, Eva d'Hennezel, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo
Published 2019-07-01

Enhanced Anticancer Effect of a Combination of S-adenosylmethionine (SAM) and Immune Checkpoint Inhibitor (ICPi) in a Syngeneic Mouse Model of Advanced Melanoma

by Ali Mehdi, Ali Mehdi, Ali Mehdi, Mikhael Attias, Mikhael Attias, Niaz Mahmood, Niaz Mahmood, Niaz Mahmood, Ani Arakelian, Ani Arakelian, Catalin Mihalcioiu, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo, Moshe Szyf, Shafaat Ahmed Rabbani, Shafaat Ahmed Rabbani, Shafaat Ahmed Rabbani, Shafaat Ahmed Rabbani, Shafaat Ahmed Rabbani
Published 2020-09-01

The Interactions between Innate Immunity and Microbiota in Gastrointestinal Diseases

by Danilo Pagliari, Ciriaco A. Piccirillo, Anis Larbi, Rossella Cianci
Published 2015-01-01

The Intricate Link among Gut “Immunological Niche,” Microbiota, and Xenobiotics in Intestinal Pathology

by Danilo Pagliari, Giovanni Gambassi, Ciriaco A. Piccirillo, Rossella Cianci
Published 2017-01-01

Immune regulation in T1D and T2D: prospective role of Foxp3+ Treg cells in disease pathogenesis and treatment

by Mara eKornete, Edward eMason, Ciriaco A Piccirillo
Published 2013-06-01

The Microbiota and Immune System Crosstalk in Health and Disease

by Rossella Cianci, Danilo Pagliari, Ciriaco A. Piccirillo, Jörg H. Fritz, Giovanni Gambassi
Published 2018-01-01

Th1-Like ICOS+ Foxp3+ Treg Cells Preferentially Express CXCR3 and Home to β-Islets during Pre-Diabetes in BDC2.5 NOD Mice.

by Mara Kornete, Edward S Mason, Julien Girouard, Erin I Lafferty, Salman Qureshi, Ciriaco A Piccirillo
Published 2015-01-01

Mesenchymal stromal cells improve salivary function and reduce lymphocytic infiltrates in mice with Sjögren's-like disease.

by Saeed Khalili, Younan Liu, Mara Kornete, Nienke Roescher, Shohta Kodama, Alan Peterson, Ciriaco A Piccirillo, Simon D Tran
Published 2012-01-01

Inflammation-driven reprogramming of CD4+ Foxp3+ regulatory T cells into pathogenic Th1/Th17 T effectors is abrogated by mTOR inhibition in vivo.

by Ekaterina Yurchenko, Marina T Shio, Tony C Huang, Maria Da Silva Martins, Moshe Szyf, Megan K Levings, Martin Olivier, Ciriaco A Piccirillo
Published 2012-01-01

Distinct translational control in CD4+ T cell subsets.

by Eva Bjur, Ola Larsson, Ekaterina Yurchenko, Lei Zheng, Valentina Gandin, Ivan Topisirovic, Shui Li, Carston R Wagner, Nahum Sonenberg, Ciriaco A Piccirillo
Published 2013-05-01

Sexual dimorphism and the role of estrogen in the immune microenvironment of liver metastases

by Simon Milette, Masakazu Hashimoto, Stephanie Perrino, Shu Qi, Michely Chen, Boram Ham, Ni Wang, Roman Istomine, Andrew M. Lowy, Ciriaco A. Piccirillo, Pnina Brodt
Published 2019-12-01

Induction of regulatory T cells by intravenous immunoglobulin: a bridge between adaptive and innate immunity

by Gabriel Nathan Kaufman, Amir Hossein Massoud, Amir Hossein Massoud, Marieme eDembele, Madelaine eYona, Ciriaco A Piccirillo, Bruce David Mazer, Bruce David Mazer
Published 2015-09-01

Salt Sensing by Serum/Glucocorticoid-Regulated Kinase 1 Promotes Th17-like Inflammatory Adaptation of Foxp3+ Regulatory T Cells

by Yujian H. Yang, Roman Istomine, Fernando Alvarez, Tho-Alfakar Al-Aubodah, Xiang Qun Shi, Tomoko Takano, Angela M. Thornton, Ethan M. Shevach, Ji Zhang, Ciriaco A. Piccirillo
Published 2020-02-01

Targeting the mTOR pathway uncouples the efficacy and toxicity of PD-1 blockade in renal transplantation

by Khashayar Esfahani, Tho-Alfakar Al-Aubodah, Pamela Thebault, Réjean Lapointe, Marie Hudson, Nathalie A. Johnson, Dana Baran, Najwa Bhulaiga, Tomoko Takano, Jean-François Cailhier, Ciriaco A. Piccirillo, Wilson H. Miller
Published 2019-10-01

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization

by Anke Fuchs, Mateusz Gliwiński, Nathali Grageda, Rachel Spiering, Abul K. Abbas, Silke Appel, Rosa Bacchetta, Manuela Battaglia, David Berglund, Bruce Blazar, Jeffrey A. Bluestone, Martin Bornhäuser, Anja ten Brinke, Todd M. Brusko, Nathalie Cools, Maria Cristina Cuturi, Edward Geissler, Nick Giannoukakis, Karolina Gołab, David A. Hafler, S. Marieke van Ham, Joanna Hester, Keli Hippen, Mauro Di Ianni, Natasa Ilic, John Isaacs, John Isaacs, Fadi Issa, Dorota Iwaszkiewicz-Grześ, Elmar Jaeckel, Irma Joosten, David Klatzmann, Hans Koenen, Cees van Kooten, Olle Korsgren, Olle Korsgren, Karsten Kretschmer, Karsten Kretschmer, Megan Levings, Natalia Maria Marek-Trzonkowska, Marc Martinez-Llordella, Djordje Miljkovic, Kingston H.G. Mills, Joana P. Miranda, Ciriaco A. Piccirillo, Amy L. Putnam, Thomas Ritter, Maria Grazia Roncarolo, Shimon Sakaguchi, Silvia Sánchez-Ramón, Birgit Sawitzki, Ljiljana Sofronic-Milosavljevic, Megan Sykes, Qizhi Tang, Marta Vives-Pi, Herman Waldmann, Piotr Witkowski, Kathryn J. Wood, Silvia Gregori, Catharien M. U. Hilkens, Giovanna Lombardi, Phillip Lord, Eva M. Martinez-Caceres, Piotr Trzonkowski
Published 2018-01-01