SPARC overexpression inhibits cell proliferation in neuroblastoma and is partly mediated by tumor suppressor protein PTEN and AKT.

by Praveen Bhoopathi, Bharathi Gorantla, G S Sailaja, Christopher S Gondi, Meena Gujrati, Jeffrey D Klopfenstein, Jasti S Rao
Published 2012-01-01

Suppression of uPA and uPAR attenuates angiogenin mediated angiogenesis in endothelial and glioblastoma cell lines.

by Hari Raghu, Sajani S Lakka, Christopher S Gondi, Sanjeeva Mohanam, Dzung H Dinh, Meena Gujrati, Jasti S Rao
Published 2010-08-01

Apoptosis induced by knockdown of uPAR and MMP-9 is mediated by inactivation of EGFR/STAT3 signaling in medulloblastoma.

by Ramaprasada Rao Kotipatruni, Arun Kumar Nalla, Swapna Asuthkar, Christopher S Gondi, Dzung H Dinh, Jasti S Rao
Published 2012-01-01

Correction: Downregulation of uPAR and Cathepsin B Induces Apoptosis via Regulation of Bcl-2 and Bax and Inhibition of the PI3K/Akt Pathway in Gliomas

by Ramarao Malla, Sreelatha Gopinath, Kiranmai Alapati, Christopher S. Gondi, Meena Gujrati, Dzung H. Dinh, Sanjeeva Mohanam, Jasti S. Rao
Published 2014-01-01

Downregulation of uPAR and cathepsin B induces apoptosis via regulation of Bcl-2 and Bax and inhibition of the PI3K/Akt pathway in gliomas.

by Ramarao Malla, Sreelatha Gopinath, Kiranmai Alapati, Christopher S Gondi, Meena Gujrati, Dzung H Dinh, Sanjeeva Mohanam, Jasti S Rao
Published 2010-10-01

Correction: Downregulation of uPAR and Cathepsin B Induces Apoptosis via Regulation of Bcl-2 and Bax and Inhibition of the PI3K/Akt Pathway in Gliomas.

by Ramarao Malla, Sreelatha Gopinath, Kiranmai Alapati, Christopher S. Gondi, Meena Gujrati, Dzung H. Dinh, Sanjeeva Mohanam, Jasti S. Rao
Published 2014-01-01

Regulation of glioblastoma progression by cord blood stem cells is mediated by downregulation of cyclin D1.

by Kiran Kumar Velpula, Venkata Ramesh Dasari, Andrew J Tsung, Christopher S Gondi, Jeffrey D Klopfenstein, Sanjeeva Mohanam, Jasti S Rao
Published 2011-03-01

Co-depletion of cathepsin B and uPAR induces G0/G1 arrest in glioma via FOXO3a mediated p27 upregulation.

by Sreelatha Gopinath, Rama Rao Malla, Christopher S Gondi, Kiranmai Alapati, Daniel Fassett, Jeffrey D Klopfenstein, Dzung H Dinh, Meena Gujrati, Jasti S Rao
Published 2010-07-01

MMP-9, uPAR and cathepsin B silencing downregulate integrins in human glioma xenograft cells in vitro and in vivo in nude mice.

by Krishna Kumar Veeravalli, Chandramu Chetty, Shivani Ponnala, Christopher S Gondi, Sajani S Lakka, Daniel Fassett, Jeffrey D Klopfenstein, Dzung H Dinh, Meena Gujrati, Jasti S Rao
Published 2010-07-01