Interrogation of the Burkholderia pseudomallei genome to address differential virulence among isolates.

by Jean F Challacombe, Chris J Stubben, Christopher P Klimko, Susan L Welkos, Steven J Kern, Joel A Bozue, Patricia L Worsham, Christopher K Cote, Daniel N Wolfe
Published 2014-01-01

Characterization of Burkholderia pseudomallei Strains Using a Murine Intraperitoneal Infection Model and In Vitro Macrophage Assays.

by Susan L Welkos, Christopher P Klimko, Steven J Kern, Jeremy J Bearss, Joel A Bozue, Robert C Bernhards, Sylvia R Trevino, David M Waag, Kei Amemiya, Patricia L Worsham, Christopher K Cote
Published 2015-01-01

Anthrax toxin component, Protective Antigen, protects insects from bacterial infections.

by Saleem Alameh, Gloria Bartolo, Summer O'Brien, Elizabeth A Henderson, Leandra O Gonzalez, Stella Hartmann, Christopher P Klimko, Jennifer L Shoe, Christopher K Cote, Laurence K Grill, Anastasia Levitin, Mikhail Martchenko Shilman
Published 2020-08-01

Evolution of Antibiotic Resistance in Surrogates of Francisella tularensis (LVS and Francisella novicida): Effects on Biofilm Formation and Fitness

by Fabrice V. Biot, Beth A. Bachert, Kevin D. Mlynek, Ronald G. Toothman, Galina I. Koroleva, Sean P. Lovett, Christopher P. Klimko, Gustavo F. Palacios, Christopher K. Cote, Jason T. Ladner, Joel A. Bozue
Published 2020-10-01

The Impact of Age and Sex on Mouse Models of Melioidosis

by Christopher P. Klimko, Sylvia R. Treviño, Alicia M. Moreau, Michael J. Aponte Cuadrado, Joshua R. Meyer, David P. Fetterer, Susan L. Welkos, Patricia L. Worsham, Norman Kreiselmeier, Carl Soffler, Christopher K. Cote
Published 2020-02-01

A Francisella novicida Mutant, Lacking the Soluble Lytic Transglycosylase Slt, Exhibits Defects in Both Growth and Virulence

by Beth A. Bachert, Sergei S. Biryukov, Jennifer Chua, Sabrina A. Rodriguez, Ronald G. Toothman, Christopher K. Cote, Christopher P. Klimko, Melissa Hunter, Jennifer L. Shoe, Janice A. Williams, Kathleen A. Kuehl, Fabrice V. Biot, Joel A. Bozue
Published 2019-06-01

Comparative virulence of three different strains of Burkholderia pseudomallei in an aerosol non-human primate model.

by Sylvia R Trevino, Jennifer L Dankmeyer, David P Fetterer, Christopher P Klimko, Jo Lynne W Raymond, Alicia M Moreau, Carl Soffler, David M Waag, Patricia L Worsham, Kei Amemiya, Sara I Ruiz, Christopher K Cote, Teresa Krakauer
Published 2021-02-01

Development, Phenotypic Characterization and Genomic Analysis of a Francisella tularensis Panel for Tularemia Vaccine Testing

by Beth A. Bachert, Joshua B. Richardson, Kevin D. Mlynek, Christopher P. Klimko, Ronald G. Toothman, David P. Fetterer, Andrea E. Luquette, Kitty Chase, Jessica L. Storrs, Ashley K. Rogers, Christopher K. Cote, David A. Rozak, Joel A. Bozue
Published 2021-08-01

Phenotypic characterization of a novel virulence-factor deletion strain of Burkholderia mallei that provides partial protection against inhalational glanders in mice

by Joel A. Bozue, Sidhartha eChaudhury, Kei eAmemiya, Jennifer eChua, Christopher K. Cote, Ronald G. Toothman, Jennifer L. Dankmeyer, Christopher P. Klimko, Catherine L. Wilhelmsen, Jolynn W. Raymond, Nela eZavaljevski, Jaques eReifman, Anders eWallqvist
Published 2016-02-01

Protection Elicited by Attenuated Live <i>Yersinia pestis</i> Vaccine Strains Against Lethal Infection with Virulent <i>Y. pestis</i>

by Christopher K. Cote, Sergei S. Biryukov, Christopher P. Klimko, Jennifer L. Shoe, Melissa Hunter, Raysa Rosario-Acevedo, David P. Fetterer, Krishna L. Moody, Joshua R. Meyer, Nathaniel O. Rill, Jennifer L. Dankmeyer, Patricia L. Worsham, Joel A. Bozue, Susan L. Welkos
Published 2021-02-01

Formaldehyde and Glutaraldehyde Inactivation of Bacterial Tier 1 Select Agents in Tissues

by Jennifer Chua, Joel A. Bozue, Christopher P. Klimko, Jennifer L. Shoe, Sara I. Ruiz, Christopher L. Jensen, Steven A. Tobery, Jared M. Crumpler, Donald J. Chabot, Avery V. Quirk, Melissa Hunter, David E. Harbourt, Arthur M. Friedlander, Christopher K. Cote
Published 2019-05-01

Impact of Toll-Like Receptor-Specific Agonists on the Host Immune Response to the Yersinia pestis Plague rF1V Vaccine

by Sergei Biryukov, Jennifer L. Dankmeyer, Zain Shamsuddin, Ivan Velez, Nathaniel O. Rill, Raysa Rosario-Acevedo, Christopher P. Klimko, Jennifer L. Shoe, Melissa Hunter, Michael D. Ward, Lisa H. Cazares, David P. Fetterer, Joel A. Bozue, Patricia L. Worsham, Christopher K. Cote, Kei Amemiya
Published 2021-08-01

Characterization of pathogenesis of and immune response to Burkholderia pseudomallei K96243 using both inhalational and intraperitoneal infection models in BALB/c and C57BL/6 mice.

by Jeremy J Bearss, Melissa Hunter, Jennifer L Dankmeyer, Kristen A Fritts, Christopher P Klimko, Chris H Weaver, Jennifer L Shoe, Avery V Quirk, Ronald G Toothman, Wendy M Webster, David P Fetterer, Joel A Bozue, Patricia L Worsham, Susan L Welkos, Kei Amemiya, Christopher K Cote
Published 2017-01-01

Avirulent Bacillus anthracis Strain with Molecular Assay Targets as Surrogate for Irradiation-Inactivated Virulent Spores

by Roger D. Plaut, Andrea B. Staab, Mark A. Munson, Joan S. Gebhardt, Christopher P. Klimko, Avery V. Quirk, Christopher K. Cote, Tony L. Buhr, Rebecca D. Rossmaier, Robert C. Bernhards, Courtney E. Love, Kimberly L. Berk, Teresa G. Abshire, David A. Rozak, Linda C. Beck, Scott Stibitz, Bruce G. Goodwin, Michael A. Smith, Shanmuga Sozhamannan
Published 2018-04-01

Disease progression in mice exposed to low-doses of aerosolized clinical isolates of Burkholderia pseudomallei.

by Sylvia R Trevino, Christopher P Klimko, Matthew C Reed, Michael J Aponte-Cuadrado, Melissa Hunter, Jennifer L Shoe, Joshua R Meyer, Jennifer L Dankmeyer, Sergei S Biryukov, Avery V Quirk, Kristen A Fritts, Steven J Kern, David P Fetterer, Lara J Kohler, Ronald G Toothman, Joel A Bozue, Christopher W Schellhase, Norman Kreiselmeier, Sharon P Daye, Susan L Welkos, Carl Soffler, Patricia L Worsham, David M Waag, Kei Amemiya, Christopher K Cote
Published 2018-01-01