Opportunities and perspectives for developing orexin receptor antagonists

by Michel Alexander Steiner, Christopher J Winrow
Published 2014-06-01

Evidence for orexinergic mechanisms in migraine

by Jan Hoffmann, Weera Supronsinchai, Simon Akerman, Anna P. Andreou, Christopher J. Winrow, John Renger, Richard Hargreaves, Peter J. Goadsby
Published 2015-02-01

Orexin receptor antagonist-induced sleep does not impair the ability to wake in response to emotionally salient acoustic stimuli in dogs

by Pamela L. Tannenbaum, Joanne eStevens, Jacquelyn eBinns, Alan eSavitz, Susan L Garson, Steven V Fox, Paul eColeman, Scott D Kuduk, Anthony L Gotter, Michael eMarino, Spencer J Tye, Jason eUslaner, Christopher J Winrow, John J Renger
Published 2014-05-01

The CNS-penetrant soluble guanylate cyclase stimulator CYR119 attenuates markers of inflammation in the central nervous system

by Susana S. Correia, Guang Liu, Sarah Jacobson, Sylvie G. Bernier, Jenny V. Tobin, Chad D. Schwartzkopf, Emily Atwater, Elisabeth Lonie, Sam Rivers, Andrew Carvalho, Peter Germano, Kim Tang, Rajesh R. Iyengar, Mark G. Currie, John R. Hadcock, Christopher J. Winrow, Juli E. Jones
Published 2021-09-01

Uncovering the genetic landscape for multiple sleep-wake traits.

by Christopher J Winrow, Deanna L Williams, Andrew Kasarskis, Joshua Millstein, Aaron D Laposky, He S Yang, Karrie Mrazek, Lili Zhou, Joseph R Owens, Daniel Radzicki, Fabian Preuss, Eric E Schadt, Kazuhiro Shimomura, Martha H Vitaterna, Chunsheng Zhang, Kenneth S Koblan, John J Renger, Fred W Turek
Published 2009-01-01

The CNS-Penetrant Soluble Guanylate Cyclase Stimulator CY6463 Reveals its Therapeutic Potential in Neurodegenerative Diseases

by Susana S. Correia, Rajesh R. Iyengar, Peter Germano, Kim Tang, Sylvie G. Bernier, Chad D. Schwartzkopf, Jenny Tobin, Thomas W.-H. Lee, Guang Liu, Sarah Jacobson, Andrew Carvalho, Glen R. Rennie, Joon Jung, Paul A. Renhowe, Elisabeth Lonie, Christopher J. Winrow, John R. Hadcock, Juli E. Jones, Mark G. Currie
Published 2021-05-01

Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulator...

by Andres D. Ramirez, Anthony L. Gotter, Steven V. Fox, Pamela L. Tannenbaum, Lihang eYao, Spencer J. Tye, Terrence eMcDonald, Joseph eBrunner, Susan L. Garson, Duane R. Reiss, Scott D. Kuduk, Paul J. Coleman, Jason M. Uslaner, Robert eHodgson, Susan E. Browne, John J. Renger, Christopher J. Winrow
Published 2013-12-01