PiZ mouse liver accumulates polyubiquitin conjugates that associate with catalytically active 26S proteasomes.

by Christopher J Haddock, Keith Blomenkamp, Madhav Gautam, Jared James, Joanna Mielcarska, Edward Gogol, Jeffrey Teckman, Dorota Skowyra
Published 2014-01-01

Kinase-dead ATM protein is highly oncogenic and can be preferentially targeted by Topo-isomerase I inhibitors

by Kenta Yamamoto, Jiguang Wang, Lisa Sprinzen, Jun Xu, Christopher J Haddock, Chen Li, Brian J Lee, Denis G Loredan, Wenxia Jiang, Alessandro Vindigni, Dong Wang, Raul Rabadan, Shan Zha
Published 2016-06-01