Suppression of galactosylceramidase (GALC) expression in the twitcher mouse model of globoid cell leukodystrophy (GLD) is caused by nonsense-mediated mRNA decay (NMD)

by Wing C. Lee, Yuen K. Tsoi, Chad A. Dickey, Michael W. DeLucia, Dennis W. Dickson, Christopher B. Eckman
Published 2006-08-01

Flemish and Dutch Mutations in Amyloid β Precursor Protein Have Different Effects on Amyloid β Secretion

by Chris De Jonghe, Cynthia Zehr, Debra Yager, Cristian-Mihail Prada, Steven Younkin, Lydia Hendriks, Christine Van Broeckhoven, Christopher B. Eckman
Published 1998-10-01

Additive Effects of PS1 and APP Mutations on Secretion of the 42-Residue Amyloid β-Protein

by Martin Citron, Christopher B. Eckman, Thekla S. Diehl, Chris Corcoran, Beth L. Ostaszewski, Weiming Xia, Georges Levesque, Peter St. George Hyslop, Steven G. Younkin, Dennis J. Selkoe
Published 1998-08-01

Evidence of a novel mechanism for partial γ-secretase inhibition induced paradoxical increase in secreted amyloid β protein.

by Eliza Barnwell, Vasudevaraju Padmaraju, Robert Baranello, Javier Pacheco-Quinto, Craig Crosson, Zsolt Ablonczy, Elizabeth Eckman, Christopher B Eckman, Viswanathan Ramakrishnan, Nigel H Greig, Miguel A Pappolla, Kumar Sambamurti
Published 2014-01-01