Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation

by Lindsey Araujo, Phillip Khim, Haik Mkhikian, Christie-Lynn Mortales, Michael Demetriou
Published 2017-01-01

N-Glycan Branching Decouples B Cell Innate and Adaptive Immunity to Control Inflammatory Demyelination

by Christie-Lynn Mortales, Sung-Uk Lee, Armen Manousadjian, Ken L. Hayama, Michael Demetriou
Published 2020-08-01

Increasing cell permeability of N-acetylglucosamine via 6-acetylation enhances capacity to suppress T-helper 1 (TH1)/TH17 responses and autoimmunity.

by Sung-Uk Lee, Carey F Li, Christie-Lynn Mortales, Judy Pawling, James W Dennis, Ani Grigorian, Michael Demetriou, Michael Demetriou
Published 2019-01-01

Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis

by Haik Mkhikian, Christie-Lynn Mortales, Raymond W Zhou, Khachik Khachikyan, Gang Wu, Stuart M Haslam, Patil Kavarian, Anne Dell, Michael Demetriou
Published 2016-06-01