Comparative Studies on the Human Serum Albumin Binding of the Investigational EGFR Inhibitor KP2187, Its Hypoxia-Activated Cobalt Complex, and a Series of Clinically Approved Inhib...

by Eva Anna Enyedy, Orsolya Dömötör, Attila Borics, Bernhard K. Keppler, Christian R. Kowol
Published 2019-08-01

Reactive Oxygen Species (ROS)-Sensitive Prodrugs of the Tyrosine Kinase Inhibitor Crizotinib

by Bjoern Bielec, Isabella Poetsch, Esra Ahmed, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol
Published 2020-03-01

Lysosomal Sequestration Impairs the Activity of the Preclinical FGFR Inhibitor PD173074

by Bernhard Englinger, Sebastian Kallus, Julia Senkiv, Anna Laemmerer, Patrick Moser, Lisa Gabler, Diana Groza, Christian R. Kowol, Petra Heffeter, Michael Grusch, Walter Berger
Published 2018-12-01

Intrinsic fluorescence of the clinically approved multikinase inhibitor nintedanib reveals lysosomal sequestration as resistance mechanism in FGFR-driven lung cancer

by Bernhard Englinger, Sebastian Kallus, Julia Senkiv, Daniela Heilos, Lisa Gabler, Sushilla van Schoonhoven, Alessio Terenzi, Patrick Moser, Christine Pirker, Gerald Timelthaler, Walter Jäger, Christian R. Kowol, Petra Heffeter, Michael Grusch, Walter Berger
Published 2017-09-01

Bacterial ghosts as adjuvant to oxaliplatin chemotherapy in colorectal carcinomatosis

by Diana Groza, Sebastian Gehrig, Pavol Kudela, Martin Holcmann, Christine Pirker, Carina Dinhof, Hemma H. Schueffl, Marek Sramko, Julia Hoebart, Fatih Alioglu, Michael Grusch, Manfred Ogris, Werner Lubitz, Bernhard K. Keppler, Irena Pashkunova-Martic, Christian R. Kowol, Maria Sibilia, Walter Berger, Petra Heffeter
Published 2018-05-01