Chemo-immunotherapy improves long-term survival in a preclinical model of MMR-D-related cancer

by Claudia Maletzki, Leonie Wiegele, Ingy Nassar, Jan Stenzel, Christian Junghanss
Published 2019-01-01

Cyclin-Dependent Kinase Inhibitors in Hematological Malignancies—Current Understanding, (Pre-)Clinical Application and Promising Approaches

by Anna Richter, Nina Schoenwaelder, Sina Sender, Christian Junghanss, Claudia Maletzki
Published 2021-05-01

Aortic valve and coronary artery bypass surgery in a patient with factor VII deficiency

by Larissa Henze, Christian Junghanss, Alper Öner, Pascal M Dohmen, Anthony Alozie
Published 2021-01-01

In vivo vaccination with cell line-derived whole tumor lysates: neoantigen quality, not quantity matters

by Inken Salewski, Yvonne Saara Gladbach, Steffen Kuntoff, Nina Irmscher, Olga Hahn, Christian Junghanss, Claudia Maletzki
Published 2020-10-01

Arginine-Depleting Enzymes – An Increasingly Recognized Treatment Strategy for Therapy-Refractory Malignancies

by Christin Riess, Fatemeh Shokraie, Carl Friedrich Classen, Bernd Kreikemeyer, Tomas Fiedler, Christian Junghanss, Claudia Maletzki
Published 2018-11-01

Unraveling the Heterogeneous Mutational Signature of Spontaneously Developing Tumors in MLH1^−/− Mice

by Yvonne Saara Gladbach, Leonie Wiegele, Mohamed Hamed, Anna-Marie Merkenschläger, Georg Fuellen, Christian Junghanss, Claudia Maletzki
Published 2019-10-01

Precursor B-ALL Cell Lines Differentially Respond to SYK Inhibition by Entospletinib

by Sina Sender, Anett Sekora, Simon Villa Perez, Oleksandra Chabanovska, Annegret Becker, Anaclet Ngezahayo, Christian Junghanss, Hugo Murua Escobar
Published 2021-01-01

Ultradeep targeted sequencing reveals low allele frequencies of somatic JAK2 and MPL variants in patients with abdominal vein thromboses: results of an ongoing prospective prevalen...

by Luise Grunwald, Christina Grosse-Thie, Sina Sender, Gudrun Knuebel, Saskia Krohn, Catrin Roolf, Christian Junghanss, Larissa Henze, Hugo Murua Escobar
Published 2020-12-01

Combined Gemcitabine and Immune-Checkpoint Inhibition Conquers Anti-PD-L1 Resistance in Low-Immunogenic Mismatch Repair-Deficient Tumors

by Inken Salewski, Julia Henne, Leonie Engster, Bjoern Schneider, Heiko Lemcke, Anna Skorska, Peggy Berlin, Larissa Henze, Christian Junghanss, Claudia Maletzki
Published 2021-06-01

Influence of Casein kinase II inhibitor CX-4945 on BCL6-mediated apoptotic signaling in B-ALL in vitro and in vivo

by Anna Richter, Sina Sender, Annemarie Lenz, Rico Schwarz, Burkhard Hinz, Gudrun Knuebel, Anett Sekora, Hugo Murua Escobar, Christian Junghanss, Catrin Roolf
Published 2020-03-01

Combined Application of Pan-AKT Inhibitor MK-2206 and BCL-2 Antagonist Venetoclax in B-Cell Precursor Acute Lymphoblastic Leukemia

by Anna Richter, Elisabeth Fischer, Clemens Holz, Julia Schulze, Sandra Lange, Anett Sekora, Gudrun Knuebel, Larissa Henze, Catrin Roolf, Hugo Murua Escobar, Christian Junghanss
Published 2021-03-01

Establishment and characterization of stable red, far-red (fR) and near infra-red (NIR) transfected canine prostate cancer cell lines

by Wen Liu, Sina Sender, Weibo Kong, Julia Beck, Anett Sekora, Kirsten Bornemann-Kolatzki, Ekkehart Schuetz, Christian Junghanss, Bertram Brenig, Ingo Nolte, Hugo Murua Escobar
Published 2020-04-01

Feasibility and Effects of a Supervised Exercise Program Suitable for Independent Training at Home on Physical Function and Quality of Life in Head and Neck Cancer Patients: A Pilo...

by Sabine Felser PhD, Martin Behrens PhD, Jan Liese MD, DDS, Daniel Fabian Strueder MD, Kirsten Rhode, Christian Junghanss MD, Christina Grosse-Thie MD
Published 2020-05-01

Isoquinolinamine FX-9 Exhibits Anti-Mitotic Activity in Human and Canine Prostate Carcinoma Cell Lines

by Jan Torben Schille, Ingo Nolte, Eva-Maria Packeiser, Laura Wiesner, Jens Ingo Hein, Franziska Weiner, Xiao-Feng Wu, Matthias Beller, Christian Junghanss, Hugo Murua Escobar
Published 2019-11-01

The Individual Effects of Cyclin-Dependent Kinase Inhibitors on Head and Neck Cancer Cells—A Systematic Analysis

by Nina Schoenwaelder, Inken Salewski, Nadja Engel, Mareike Krause, Björn Schneider, Michael Müller, Christin Riess, Heiko Lemcke, Anna Skorska, Christina Grosse-Thie, Christian Junghanss, Claudia Maletzki
Published 2021-05-01

Evaluation of Choroidal Melanoma Vascularization by Color Doppler Flow Imaging: An Option for Follow-Up Tumor Control Assessment after CyberKnife^®?

by Cinja Kaak, Vinodh Kakkassery, Björn O. Scheef, Marco Zschoche, Felix Rommel, Guido Hildebrandt, Steffen Emmert, Christian Junghanß, Rudolf F. Guthoff, Anselm M. Jünemann, Uwe Walter
Published 2021-05-01

Reduced adolescent-age spatial learning ability associated with elevated juvenile-age superoxide levels in complex I mouse mutants.

by Johannes Mayer, Gesine Reichart, Tursonjan Tokay, Falko Lange, Simone Baltrusch, Christian Junghanss, Olaf Wolkenhauer, Robert Jaster, Manfred Kunz, Markus Tiedge, Saleh Ibrahim, Georg Fuellen, Rüdiger Köhling
Published 2015-01-01

Combined Casein Kinase II inhibition and epigenetic modulation in acute B-lymphoblastic leukemia

by Anna Richter, Catrin Roolf, Mohamed Hamed, Yvonne Saara Gladbach, Sina Sender, Christoph Konkolefski, Gudrun Knübel, Anett Sekora, Georg Fuellen, Brigitte Vollmar, Hugo Murua Escobar, Christian Junghanss
Published 2019-03-01

Prognostic Role of Circulating Tumor Cells during Induction Chemotherapy Followed by Curative Surgery Combined with Postoperative Radiotherapy in Patients with Locally Advanced Ora...

by Johanna Inhestern, Katrin Oertel, Viola Stemmann, Harald Schmalenberg, Andreas Dietz, Nicole Rotter, Johannes Veit, Martin Görner, Holger Sudhoff, Christian Junghanß, Claus Wittekindt, Katharina Pachmann, Orlando Guntinas-Lichius
Published 2015-01-01

Activation of the Kynurenine Pathway in Human Malignancies Can Be Suppressed by the Cyclin-Dependent Kinase Inhibitor Dinaciclib

by Christin Riess, Christin Riess, Christin Riess, Björn Schneider, Hanna Kehnscherper, Julia Gesche, Nina Irmscher, Fatemeh Shokraie, Carl Friedrich Classen, Elisa Wirthgen, Grazyna Domanska, Annette Zimpfer, Daniel Strüder, Christian Junghanss, Claudia Maletzki
Published 2020-02-01