HNSCC: Tumour Antigens and Their Targeting by Immunotherapy

by Adrian von Witzleben, Chuan Wang, Simon Laban, Natalia Savelyeva, Christian H. Ottensmeier
Published 2020-09-01

The utility of Ki-67 as a prognostic biomarker in pulmonary neuroendocrine tumours: protocol for a systematic review and meta-analysis

by Salma Naheed, Chloe Holden, Lulu Tanno, Eleanor Jaynes, Christian H Ottensmeier, Giuseppe Pelosi
Published 2019-08-01

Correction: Comparison of attitudes towards five end-of-life care interventions (active pain control, withdrawal of futile life-sustaining treatment, passive euthanasia, active eut...

by Salma Naheed, Chloe Holden, Lulu Tanno, Eleanor Jaynes, Christian H Ottensmeier, Giuseppe Pelosi
Published 2019-08-01

Correlation of HPV16 Gene Status and Gene Expression With Antibody Seropositivity and TIL Status in OPSCC

by Adrian von Witzleben, Adrian von Witzleben, Eve Currall, Oliver Wood, Lindsey Chudley, Oluyemisi Akinyegun, Jaya Thomas, Kaïdre Bendjama, Gareth J. Thomas, Gareth J. Thomas, Peter S. Friedmann, Emma V. King, Emma V. King, Simon Laban, Christian H. Ottensmeier, Christian H. Ottensmeier
Published 2021-01-01

Vaccination Expands Antigen-Specific CD4+ Memory T Cells and Mobilizes Bystander Central Memory T Cells.

by Eleonora Li Causi, Suraj C Parikh, Lindsey Chudley, David M Layfield, Christian H Ottensmeier, Freda K Stevenson, Gianfranco Di Genova
Published 2015-01-01

Mucosal-Associated Invariant T (MAIT) Cells Are Impaired in Th17 Associated Primary and Secondary Immunodeficiencies.

by Yifang Gao, William Rae, Keseva Ananth Ramakrishnan, Gabriela Barcenas-Morales, Rainer Döffinger, Efrem Eren, Saul N Faust, Christian H Ottensmeier, Anthony P Williams
Published 2016-01-01

CTEN Induces Tumour Cell Invasion and Survival and Is Prognostic in Radiotherapy-Treated Head and Neck Cancer

by Jason C. Fleming, Jeongmin Woo, Karwan Moutasim, Christopher J. Hanley, Steven J. Frampton, Oliver Wood, Matthew Ward, Christopher H Woelk, Christian H. Ottensmeier, Sassan Hafizi, Dae Kim, Gareth J. Thomas
Published 2020-10-01

Targeting gp100 and TRP-2 with a DNA vaccine: Incorporating T cell epitopes with a human IgG1 antibody induces potent T cell responses that are associated with favourable clinical...

by Poulam M. Patel, Christian H. Ottensmeier, Clive Mulatero, Paul Lorigan, Ruth Plummer, Hardev Pandha, Somaia Elsheikh, Efthymios Hadjimichael, Naty Villasanti, Sally E. Adams, Michelle Cunnell, Rachael L. Metheringham, Victoria A. Brentville, Lee Machado, Ian Daniels, Mohamed Gijon, Drew Hannaman, Lindy G. Durrant
Published 2018-06-01

Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α

by Liku B Tezera, Magdalena K Bielecka, Paul Ogongo, Naomi F Walker, Matthew Ellis, Diana J Garay-Baquero, Kristian Thomas, Michaela T Reichmann, David A Johnston, Katalin Andrea Wilkinson, Mohamed Ahmed, Sanjay Jogai, Suwan N Jayasinghe, Robert J Wilkinson, Salah Mansour, Gareth J Thomas, Christian H Ottensmeier, Alasdair Leslie, Paul T Elkington
Published 2020-02-01

Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis

by Mark G Jones, Orestis G Andriotis, James JW Roberts, Kerry Lunn, Victoria J Tear, Lucy Cao, Kjetil Ask, David E Smart, Alessandra Bonfanti, Peter Johnson, Aiman Alzetani, Franco Conforti, Regan Doherty, Chester Y Lai, Benjamin Johnson, Konstantinos N Bourdakos, Sophie V Fletcher, Ben G Marshall, Sanjay Jogai, Christopher J Brereton, Serena J Chee, Christian H Ottensmeier, Patricia Sime, Jack Gauldie, Martin Kolb, Sumeet Mahajan, Aurelie Fabre, Atul Bhaskar, Wolfgang Jarolimek, Luca Richeldi, Katherine MA O'Reilly, Phillip D Monk, Philipp J Thurner, Donna E Davies
Published 2018-07-01