Balancing sensitivity and specificity in distinguishing TCR groups by CDR sequence similarity

by Neerja Thakkar, Chris Bailey-Kellogg
Published 2019-05-01

Building blocks and blueprints for bacterial autolysins.

by Spencer J Mitchell, Deeptak Verma, Karl E Griswold, Chris Bailey-Kellogg
Published 2021-04-01

Mapping the Pareto optimal design space for a functionally deimmunized biotherapeutic candidate.

by Regina S Salvat, Andrew S Parker, Yoonjoo Choi, Chris Bailey-Kellogg, Karl E Griswold
Published 2015-01-01

Computationally-driven identification of antibody epitopes

by Casey K Hua, Albert T Gacerez, Charles L Sentman, Margaret E Ackerman, Yoonjoo Choi, Chris Bailey-Kellogg
Published 2017-12-01

Characterizing Epitope Binding Regions of Entire Antibody Panels by Combining Experimental and Computational Analysis of Antibody: Antigen Binding Competition

by Benjamin D. Brooks, Adam Closmore, Juechen Yang, Michael Holland, Tina Cairns, Gary H. Cohen, Chris Bailey-Kellogg
Published 2020-08-01

Computer-guided binding mode identification and affinity improvement of an LRR protein binder without structure determination.

by Yoonjoo Choi, Sukyo Jeong, Jung-Min Choi, Christian Ndong, Karl E Griswold, Chris Bailey-Kellogg, Hak-Sung Kim
Published 2020-08-01

Polyfunctional HIV-Specific Antibody Responses Are Associated with Spontaneous HIV Control.

by Margaret E Ackerman, Anastassia Mikhailova, Eric P Brown, Karen G Dowell, Bruce D Walker, Chris Bailey-Kellogg, Todd J Suscovich, Galit Alter
Published 2016-01-01

Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance

by Kristina Blazanovic, Hongliang Zhao, Yoonjoo Choi, Wen Li, Regina S Salvat, Daniel C Osipovitch, Jennifer Fields, Leonard Moise, Brent L Berwin, Steven N Fiering, Chris Bailey-Kellogg, Karl E Griswold
Published 2015-01-01

Machine learning methods enable predictive modeling of antibody feature:function relationships in RV144 vaccinees.

by Ickwon Choi, Amy W Chung, Todd J Suscovich, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sorachai Nitayaphan, Jaranit Kaewkungwal, Robert J O'Connell, Donald Francis, Merlin L Robb, Nelson L Michael, Jerome H Kim, Galit Alter, Margaret E Ackerman, Chris Bailey-Kellogg
Published 2015-04-01

Antibody Fab‐Fc properties outperform titer in predictive models of SIV vaccine‐induced protection

by Srivamshi Pittala, Kenneth Bagley, Jennifer A Schwartz, Eric P Brown, Joshua A Weiner, Ilia J Prado, Wenlei Zhang, Rong Xu, Ayuko Ota‐Setlik, Ranajit Pal, Xiaoying Shen, Charles Beck, Guido Ferrari, George K Lewis, Celia C LaBranche, David C Montefiori, Georgia D Tomaras, Galit Alter, Mario Roederer, Timothy R Fouts, Margaret E Ackerman, Chris Bailey‐Kellogg
Published 2019-05-01

Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge

by Todd Bradley, Justin Pollara, Sampa Santra, Nathan Vandergrift, Srivamshi Pittala, Chris Bailey-Kellogg, Xiaoying Shen, Robert Parks, Derrick Goodman, Amanda Eaton, Harikrishnan Balachandran, Linh V. Mach, Kevin O. Saunders, Joshua A. Weiner, Richard Scearce, Laura L. Sutherland, Sanjay Phogat, Jim Tartaglia, Steven G. Reed, Shiu-Lok Hu, James F. Theis, Abraham Pinter, David C. Montefiori, Thomas B. Kepler, Kristina K. Peachman, Mangala Rao, Nelson L. Michael, Todd J. Suscovich, Galit Alter, Margaret E. Ackerman, M. Anthony Moody, Hua-Xin Liao, Georgia Tomaras, Guido Ferrari, Bette T. Korber, Barton F. Haynes
Published 2017-06-01