IGF-1R Inhibition Activates a YES/SFK Bypass Resistance Pathway: Rational Basis for Co-Targeting IGF-1R and Yes/SFK Kinase in Rhabdomyosarcoma

by Xiaolin Wan, Choh Yeung, Christine Heske, Arnulfo Mendoza, Lee J. Helman
Published 2015-04-01

The Role of PDGFR-β Activation in Acquired Resistance to IGF-1R Blockade in Preclinical Models of Rhabdomyosarcoma

by Christine M. Heske, Choh Yeung, Arnulfo Mendoza, Joshua T. Baumgart, Leah D. Edessa, Xiaolin Wan, Lee J. Helman
Published 2016-12-01

Ecteinascidin 743 Interferes with the Activity of EWS-FLI1 in Ewing Sarcoma Cells

by Patrick J. Grohar, Laurie B. Griffin, Choh Yeung, Qing-Rong Chen, Yves Pommier, Chand Khanna, Javed Khan, Lee J. Helman
Published 2011-02-01