HSP70s: From Tumor Transformation to Cancer Therapy

by Chih-Wen Shu, Chun-Ming Huang Ph.D.
Published 2008-01-01

Autophagy modulation as a potential targeted cancer therapy: From drug repurposing to new drug development

by Chia‐Jung Lin, Yuan‐Ni Tsao, Chih‐Wen Shu
Published 2021-03-01

ERBB2-modulated ATG4B and autophagic cell death in human ARPE19 during oxidative stress.

by Shwu-Jiuan Sheu, Jiunn-Liang Chen, Youn-Shen Bee, Shi-Han Lin, Chih-Wen Shu
Published 2019-01-01

Differential autophagic effects of vital dyes in retinal pigment epithelial ARPE-19 and photoreceptor 661W cells.

by Shwu-Jiuan Sheu, Jiunn-Liang Chen, Youn-Shen Bee, Yi-An Chen, Shi-Han Lin, Chih-Wen Shu
Published 2017-01-01

Detection of Autophagy-Related Gene Expression by Conjunctival Impression Cytology in Age-Related Macular Degeneration

by Chih-Wen Shu, Youn-Shen Bee, Jiunn-Liang Chen, Chui-Lien Tsen, Wei-Lun Tsai, Shwu-Jiuan Sheu
Published 2021-02-01

Tumor Susceptibility Gene 101 facilitates rapamycin-induced autophagic flux in neuron cells

by Jiin-Tsuey Cheng, Pei-Feng Liu, Hsiu-Chen Yang, Shih-Ju Huang, Malcolm Griffith, Paul Morgan, Chih-Wen Shu
Published 2021-02-01

New Flavones, a 2-(2-Phenylethyl)-4H-chromen-4-one Derivative, and Anti-Inflammatory Constituents from the Stem Barks of Aquilaria sinensis

by Sin-Ling Wang, Tsong-Long Hwang, Mei-Ing Chung, Ping-Jyun Sung, Chih-Wen Shu, Ming-Jen Cheng, Jih-Jung Chen
Published 2015-11-01

Kinome-Wide siRNA Screening Identifies Src-Enhanced Resistance of Chemotherapeutic Drugs in Triple-Negative Breast Cancer Cells

by Yen-Dun Tony Tzeng, Yen-Dun Tony Tzeng, Pei-Feng Liu, Pei-Feng Liu, Ju-Yueh Li, Li-Feng Liu, Li-Feng Liu, Soong-Yu Kuo, Chiao-Wei Hsieh, Cheng-Hsin Lee, Chih-Hsuan Wu, Michael Hsiao, Michael Hsiao, Hong-Tai Chang, Chih-Wen Shu, Chih-Wen Shu
Published 2018-11-01

Kinome-Wide Screening with Small Interfering RNA Identified Polo-like Kinase 1 as a Key Regulator of Proliferation in Oral Cancer Cells

by Yih-Gang Goan, Pei-Feng Liu, Hsueh-Wei Chang, Hung-Chih Chen, Wen-Chi Chen, Shyh-Ming Kuo, Cheng-Hsin Lee, Chih-Wen Shu
Published 2019-08-01

Caffeic Acid Phenethyl Ester Rescues Pulmonary Arterial Hypertension through the Inhibition of AKT/ERK-Dependent PDGF/HIF-1α In Vitro and In Vivo

by Chin-Chang Cheng, Pei-Ling Chi, Min-Ci Shen, Chih-Wen Shu, Shue-Ren Wann, Chun-Peng Liu, Ching-Jiunn Tseng, Wei-Chun Huang
Published 2019-03-01

New Coumarins and Anti-Inflammatory Constituents from the Fruits of Cnidium monnieri

by Tzong-Huei Lee, Yuan-Chih Chen, Tsong-Long Hwang, Chih-Wen Shu, Ping-Jyun Sung, Yun-Ping Lim, Wen-Lung Kuo, Jih-Jung Chen
Published 2014-05-01

Antitumor Effects of a Sesquiterpene Derivative from Marine Sponge in Human Breast Cancer Cells

by Li-Yuan Bai, Jui-Hsin Su, Chang-Fang Chiu, Wei-Yu Lin, Jing-Lan Hu, Chia-Hsien Feng, Chih-Wen Shu, Jing-Ru Weng
Published 2021-04-01

Clinicopathological Association of Autophagy Related 5 Protein with Prognosis of Colorectal Cancer

by Wan-Hsiang Hu, Wen-Chi Yang, Pei-Feng Liu, Ting-Ting Liu, Paul Morgan, Wei-Lun Tsai, Hung-Wei Pan, Cheng-Hsin Lee, Chih-Wen Shu
Published 2021-04-01

UBE2C is a Potential Biomarker for Tumorigenesis and Prognosis in Tongue Squamous Cell Carcinoma

by Pei-Feng Liu, Chun-Feng Chen, Chih-Wen Shu, Hui-Min Chang, Cheng-Hsin Lee, Huei-Han Liou, Luo-Ping Ger, Chun-Lin Chen, Bor-Hwang Kang
Published 2020-09-01

<i>Xanthium strumarium</i> Fruit Extract Inhibits ATG4B and Diminishes the Proliferation and Metastatic Characteristics of Colorectal Cancer Cells

by Hsueh-Wei Chang, Pei-Feng Liu, Wei-Lun Tsai, Wan-Hsiang Hu, Yu-Chang Hu, Hsiu-Chen Yang, Wei-Yu Lin, Jing-Ru Weng, Chih-Wen Shu
Published 2019-06-01

TRAIL, Wnt, Sonic Hedgehog, TGFβ, and miRNA Signalings Are Potential Targets for Oral Cancer Therapy

by Ammad Ahmad Farooqi, Chih-Wen Shu, Hurng-Wern Huang, Hui-Ru Wang, Yung-Ting Chang, Sundas Fayyaz, Shyng-Shiou F. Yuan, Jen-Yang Tang, Hsueh-Wei Chang
Published 2017-07-01

Ablation of ATG4B Suppressed Autophagy and Activated AMPK for Cell Cycle Arrest in Cancer Cells

by Pei-Feng Liu, Chien-Jen Hsu, Wei-Lun Tsai, Jin-Shiung Cheng, Jih-Jung Chen, I-Fei Huang, Ho-Hsing Tseng, Hsueh-Wei Chang, Chih-Wen Shu
Published 2017-11-01

RelA-Mediated BECN1 Expression Is Required for Reactive Oxygen Species-Induced Autophagy in Oral Cancer Cells Exposed to Low-Power Laser Irradiation.

by Chih-Wen Shu, Hong-Tai Chang, Chieh-Shan Wu, Chien-Hsun Chen, Sam Wu, Hsueh-Wei Chang, Soong-Yu Kuo, Earl Fu, Pei-Feng Liu, Yao-Dung Hsieh
Published 2016-01-01

Versatile assays for high throughput screening for activators or inhibitors of intracellular proteases and their cellular regulators.

by Hideki Hayashi, Michael Cuddy, Vincent Chih-Wen Shu, Kenneth W Yip, Charitha Madiraju, Paul Diaz, Toshifumi Matsuyama, Muneshige Kaibara, Kohtaro Taniyama, Stefan Vasile, Eduard Sergienko, John C Reed
Published 2009-10-01

The MAP3K7-mTOR Axis Promotes the Proliferation and Malignancy of Hepatocellular Carcinoma Cells

by Jin-Shiung Cheng, Wei-Lun Tsai, Wei-Lun Tsai, Pei-Feng Liu, Yih-Gang Goan, Chih-Wen Lin, Chih-Wen Lin, Ho-Hsing Tseng, Cheng-Hsin Lee, Chih-Wen Shu
Published 2019-06-01