Tetramethylpyrazine (TMP) switches energy signalling from the PKCζ-GLUT4-glucose pathway back to the SIRT1-CD36-fatty acid pathway similar to resveratrol to ameliorate cardiac myoc...

by Yeh-Peng Chen, Chia-Wen Tsai, Dennis Jine-Yuan Hsieh, Chia-Yao Shen, Tsung-Jung Ho, V. Vijaya Padma, Wei- Wen Kuo, Chih-Yang Huang
Published 2015-12-01

Chemoresistance-Associated Silencing of miR-4454 Promotes Colorectal Cancer Aggression through the <i>GNL3L</i> and <i>NF-κB</i> Pathway

by Thetchinamoorthy Kannathasan, Wei-Wen Kuo, Ming-Cheng Chen, Vijaya Padma Viswanadha, Chia-Yao Shen, Chuan-Chou Tu, Yu-Lan Yeh, Mahalakshmi Bharath, Marthandam Asokan Shibu, Chih-Yang Huang
Published 2020-05-01

Lactobacillus paracasei GMNL-32 exerts a therapeutic effect on cardiac abnormalities in NZB/W F1 mice.

by Wei-Syun Hu, Peramaiyan Rajendran, Bor-Show Tzang, Yu-Lan Yeh, Chia-Yao Shen, Ray-Jade Chen, Tsung-Jung Ho, Viswanadha Vijaya Padma, Yi-Hsing Chen, Chih-Yang Huang
Published 2017-01-01

Bioactive Peptide Improves Diet-Induced Hepatic Fat Deposition and Hepatocyte Proinflammatory Response in SAMP8 Ageing Mice

by Stanley Dumeus, Marthandam Asokan Shibu, Wan-Teng Lin, Ming-Fu Wang, Chao-Hung Lai, Chia-Yao Shen, Yueh-Min Lin, Vijaya Padma Viswanadha, Wei-Wen Kuo, Chih-Yang Huang
Published 2018-08-01

Tetramethylpyrazine Ameliorated Hypoxia-Induced Myocardial Cell Apoptosis via HIF-1α/JNK/p38 and IGFBP3/BNIP3 Inhibition to Upregulate PI3K/Akt Survival Signaling

by Kuan-Ho Lin, Wei-Wen Kuo, Ai-Zhi Jiang, Peiying Pai, Jing-Ying Lin, Wei-Kung Chen, Cecilia Hsuan Day, Chia-Yao Shen, V. Vijaya Padma, Chih Yang Huang
Published 2015-05-01

17β-Estradiol and/or estrogen receptor alpha signaling blocks protein phosphatase 1 mediated ISO induced cardiac hypertrophy.

by Hsin-Yuan Fang, Meng-Yu Hung, Yueh-Min Lin, Sudhir Pandey, Chia-Chien Chang, Kuan-Ho Lin, Chia-Yao Shen, Vijaya Padma Viswanadha, Wei-Wen Kuo, Chih-Yang Huang
Published 2018-01-01

Treatment with 17β-Estradiol Reduced Body Weight and the Risk of Cardiovascular Disease in a High-Fat Diet-Induced Animal Model of Obesity

by Wei-Jen Ting, Chih-Yang Huang, Chong-He Jiang, Yueh-Min Lin, Li-Chin Chung, Chia-Yao Shen, Peiying Pai, Kuan-Ho Lin, Vijaya Padma Viswanadha, Shih-Chieh Liao
Published 2017-03-01

Bioactive flavone fisetin attenuates hypertension associated cardiac hypertrophy in H9c2 cells and in spontaneously hypertension rats

by Kuan-Ho Lin, Marthandam Asokan Shibu, Rajendran Peramaiyan, Ya-Fang Chen, Chia-Yao Shen, You-Liang Hsieh, Ray-Jade Chen, Vijaya Padma Viswanadha, Wei-Wen Kuo, Chih-Yang Huang
Published 2019-01-01

Silymarin Accelerates Liver Regeneration after Partial Hepatectomy

by Jia-Ping Wu, Chin-Chuan Tsai, Yu-Lan Yeh, Yueh-Min Lin, Chien-Chung Lin, Cecilia Hsuan Day, Chia-Yao Shen, V. Vijaya Padma, Lung-Fa Pan, Chih-Yang Huang
Published 2015-01-01

Anthocyanin Attenuates Doxorubicin-Induced Cardiomyotoxicity via Estrogen Receptor-α/β and Stabilizes HSF1 to Inhibit the IGF-IIR Apoptotic Pathway

by Pei-Chen Huang, Wei-Wen Kuo, Chia-Yao Shen, Yu-Feng Chen, Yueh-Min Lin, Tsung-Jung Ho, V. Vijaya Padma, Jeng-Fan Lo, Chih-Yang Huang, Chih-Yang Huang
Published 2016-09-01

Estrogen and/or Estrogen Receptor α Inhibits BNIP3-Induced Apoptosis and Autophagy in H9c2 Cardiomyoblast Cells

by Bih-Cheng Chen, Yi-Jiun Weng, Marthandam Asokan Shibu, Chien-Kuo Han, Yueh-Sheng Chen, Chia-Yao Shen, Yueh-Min Lin, Vijaya Padma Viswanadha, Hsin-Yueh Liang, Chih-Yang Huang
Published 2018-04-01

17β-Estradiol and/or Estrogen Receptor β Attenuate the Autophagic and Apoptotic Effects Induced by Prolonged Hypoxia Through HIF-1α-Mediated BNIP3 and IGFBP-3 Signaling Blockage

by Dennis Jine-Yuan Hsieh, Wei-Wen Kuo, Yi-Ping Lai, Marthandam Asokan Shibu, Chia-Yao Shen, Peiying Pai, Yu-Lan Yeh, Jing-Ying Lin, Vijaya Padma Viswanadha, Chih-Yang Huang
Published 2015-05-01

E2/ER β inhibit ISO-induced cardiac cellular hypertrophy by suppressing Ca2+-calcineurin signaling.

by Cheng-Yen Tsai, Wei-Wen Kuo, Marthandam Asokan Shibu, Yueh-Min Lin, Chien-Nam Liu, Yi-Hui Chen, Cecilia-Hsuan Day, Chia-Yao Shen, Vijaya Padma Viswanadha, Chih-Yang Huang
Published 2017-01-01

Anti-Apoptosis and Anti-Fibrosis Effects of Eriobotrya Japonica in Spontaneously Hypertensive Rat Hearts

by Jui-Ting Chiang, Khan Farheen Badrealam, Marthandam Asokan Shibu, Sue-Fei Cheng, Chia-Yao Shen, Chih-Feng Chang, Yueh-Min Lin, Vijaya Padma Viswanadha, Shih-Chieh Liao, Chih-Yang Huang
Published 2018-05-01

Lactobacillus reuteri GMNL-263 reduces hyperlipidaemia and the heart failure process in high-calorie diet-fed induced heart dysfunction in rats

by Po-Hsiang Liao, Wei-Wen Kuo, Chia-Hua Kuo, Yu-Lan Yeh, Chia-Yao Shen, Ya-Hui Chen, Ray-Jade Chen, V. Vijaya Padma, Yi-Hsing Chen, Chih-Yang Huang
Published 2016-01-01

Platycodin D (PD) attenuates myocardial apoptosis mediated by JNK-SIRT1-HSF1-IGF-IIR-Caspase-3 signaling in hypertensive conditions

by Yuan-Chuan Lin, Yu-Chen Lin, Wei-Wen Kuo, Chia-Yao Shen, Yu-Feng Chen, Yueh-Min Lin, Tsung-Jung Ho, V. Vijaya Padma, Chih-Yang Huang, Chih-Yang Huang
Published 2017-07-01

Protective effect of HDL on NADPH oxidase-derived super oxide anion mediates hypoxia-induced cardiomyocyte apoptosis.

by Su-Ying Wen, Shanmugam Tamilselvi, Chia-Yao Shen, Cecilia Hsuan Day, Li-Chin Chun, Li-Yi Cheng, Hsiu-Chung Ou, Ray-Jade Chen, Vijaya Padma Viswanadha, Wei-Wen Kuo, Chih-Yang Huang
Published 2017-01-01

Mesenchymal Stem Cell Insights: Prospects in Hematological Transplantation

by Shiu-Huey Chou, Shinn-Zong Lin, Cecilia Hsuan Day, Wei-Wen Kuo, Chia-Yao Shen, Dennis Jine-Yuan Hsieh, Jing-Ying Lin, Fuu-Jen Tsai, Chang-Hai Tsai, Chih-Yang Huang Ph.D.
Published 2013-04-01

Prostaglandin E2-Induced COX-2 Expressions via EP2 and EP4 Signaling Pathways in Human LoVo Colon Cancer Cells

by Hsi-Hsien Hsu, Yueh-Min Lin, Chia-Yao Shen, Marthandam Asokan Shibu, Shin-Yi Li, Sheng-Huang Chang, Chien-Chung Lin, Ray-Jade Chen, Vijaya Padma Viswanadha, Hui-Nung Shih, Chih-Yang Huang
Published 2017-05-01