Dysregulation of Protein Phosphorylation/Dephosphorylation in Alzheimer's Disease: A Therapeutic Target

by Cheng-Xin Gong, Fei Liu, Inge Grundke-Iqbal, Khalid Iqbal
Published 2006-01-01

Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 × Tg-AD mice

by Chun-ling Dai, Wen Hu, Yunn Chyn Tung, Fei Liu, Cheng-Xin Gong, Khalid Iqbal
Published 2018-01-01

Young blood plasma reduces Alzheimer’s disease-like brain pathologies and ameliorates cognitive impairment in 3×Tg-AD mice

by Ying Zhao, Ran Qian, Jin Zhang, Fei Liu, Khalid Iqbal, Chun-Ling Dai, Cheng-Xin Gong
Published 2020-06-01

Anesthesia with sevoflurane or isoflurane induces severe hypoglycemia in neonatal mice.

by Qian Yu, Jian Li, Chun-Ling Dai, Hengchang Li, Khalid Iqbal, Fei Liu, Cheng-Xin Gong
Published 2020-01-01

Dyrk1A overexpression leads to increase of 3R-tau expression and cognitive deficits in Ts65Dn Down syndrome mice

by Xiaomin Yin, Nana Jin, Jianhua Shi, Yanchong Zhang, Yue Wu, Cheng-Xin Gong, Khalid Iqbal, Fei Liu
Published 2017-04-01

Expression of Tau Pathology-Related Proteins in Different Brain Regions: A Molecular Basis of Tau Pathogenesis

by Wen Hu, Wen Hu, Feng Wu, Yanchong Zhang, Yanchong Zhang, Cheng-Xin Gong, Khalid Iqbal, Fei Liu, Fei Liu
Published 2017-09-01

Intranasal Insulin Prevents Anesthesia-Induced Cognitive Impairment and Chronic Neurobehavioral Changes

by Yanxing Chen, Yanxing Chen, Chun-Ling Dai, Zhe Wu, Zhe Wu, Khalid Iqbal, Fei Liu, Baorong Zhang, Cheng-Xin Gong
Published 2017-05-01

Developmental regulation of protein O-GlcNAcylation, O-GlcNAc transferase, and O-GlcNAcase in mammalian brain.

by Ying Liu, Xiaojing Li, Yang Yu, Jianhua Shi, Zhihou Liang, Xiaoqin Run, Yi Li, Chun-ling Dai, Inge Grundke-Iqbal, Khalid Iqbal, Fei Liu, Cheng-Xin Gong
Published 2012-01-01

Relevance of Phosphorylation and Truncation of Tau to the Etiopathogenesis of Alzheimer’s Disease

by Yan Zhou, Yan Zhou, Yan Zhou, Jianhua Shi, Jianhua Shi, Dandan Chu, Wen Hu, Wen Hu, Zongyu Guan, Cheng-Xin Gong, Khalid Iqbal, Fei Liu, Fei Liu
Published 2018-02-01

Brain gene expression of a sporadic (icv-STZ Mouse) and a familial mouse model (3xTg-AD mouse) of Alzheimer's disease.

by Yanxing Chen, Zhu Tian, Zhihou Liang, Shenggang Sun, Chun-Ling Dai, Moon H Lee, Frank M LaFerla, Inge Grundke-Iqbal, Khalid Iqbal, Fei Liu, Cheng-Xin Gong
Published 2012-01-01

Alzheimer’s disease brain contains tau fractions with differential prion-like activities

by Longfei Li, Ruirui Shi, Jianlan Gu, Yunn Chyn Tung, Yan Zhou, Dingwei Zhou, Ruozhen Wu, Dandan Chu, Nana Jin, Kevin Deng, Jiawei Xu, Cheng-Xin Gong, Khalid Iqbal, Fei Liu
Published 2021-02-01

Differential effects of an O-GlcNAcase inhibitor on tau phosphorylation.

by Yang Yu, Lan Zhang, Xiaojing Li, Xiaoqin Run, Zhihou Liang, Yi Li, Ying Liu, Moon H Lee, Inge Grundke-Iqbal, Khalid Iqbal, David J Vocadlo, Fei Liu, Cheng-Xin Gong
Published 2012-01-01

Intranasal Administration of Insulin Reduces Chronic Behavioral Abnormality and Neuronal Apoptosis Induced by General Anesthesia in Neonatal Mice

by Hengchang Li, Hengchang Li, Chun-ling Dai, Jin-Hua Gu, Jin-Hua Gu, Shengwei Peng, Shengwei Peng, Jian Li, Jian Li, Qian Yu, Qian Yu, Khalid Iqbal, Fei Liu, Cheng-Xin Gong
Published 2019-07-01

Pathological Tau From Alzheimer’s Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivo

by Jin Miao, Jin Miao, Jin Miao, Ruirui Shi, Ruirui Shi, Longfei Li, Longfei Li, Feng Chen, Feng Chen, Yan Zhou, Yan Zhou, Yunn Chyn Tung, Wen Hu, Cheng-Xin Gong, Khalid Iqbal, Fei Liu
Published 2019-03-01