Optogenetic TDP-43 nucleation induces persistent insoluble species and progressive motor dysfunction in vivo

by Charlton G. Otte, Tyler R. Fortuna, Jacob R. Mann, Amanda M. Gleixner, Nandini Ramesh, Noah J. Pyles, Udai B. Pandey, Christopher J. Donnelly
Published 2020-12-01

Drosophila Ref1/ALYREF regulates transcription and toxicity associated with ALS/FTD disease etiologies

by Amit Berson, Lindsey D. Goodman, Ashley N. Sartoris, Charlton G. Otte, James A. Aykit, Virginia M.-Y. Lee, John Q. Trojanowski, Nancy M. Bonini
Published 2019-04-01