Non-equilibrium repressor binding kinetics link DNA damage dose to transcriptional timing within the SOS gene network.

by Matthew J Culyba, Jeffrey M Kubiak, Charlie Y Mo, Mark Goulian, Rahul M Kohli
Published 2018-06-01

Advancement of the 5-Amino-1-(Carbamoylmethyl)-1H-1,2,3-Triazole-4-Carboxamide Scaffold to Disarm the Bacterial SOS Response

by Trevor Selwood, Trevor Selwood, Brian J. Larsen, Charlie Y. Mo, Charlie Y. Mo, Matthew J. Culyba, Matthew J. Culyba, Zachary M. Hostetler, Zachary M. Hostetler, Rahul M. Kohli, Rahul M. Kohli, Allen B. Reitz, Simon D. P. Baugh
Published 2018-12-01

Systematically Altering Bacterial SOS Activity under Stress Reveals Therapeutic Strategies for Potentiating Antibiotics

by Charlie Y. Mo, Sara A. Manning, Manuela Roggiani, Matthew J. Culyba, Amanda N. Samuels, Paul D. Sniegowski, Mark Goulian, Rahul M. Kohli, Paul Dunman
Published 2016-08-01