Innate sensing of chitin and chitosan.

by Chelsea L Bueter, Charles A Specht, Stuart M Levitz
Published 2013-01-01

Vaccines for human fungal diseases: close but still a long way to go

by Lorena V. N. Oliveira, Ruiying Wang, Charles A. Specht, Stuart M. Levitz
Published 2021-03-01

Gene families of cuticular proteins analogous to peritrophins (CPAPs) in Tribolium castaneum have diverse functions.

by Sinu Jasrapuria, Charles A Specht, Karl J Kramer, Richard W Beeman, Subbaratnam Muthukrishnan
Published 2012-01-01

Induction of Protective Immunity to Cryptococcal Infection in Mice by a Heat-Killed, Chitosan-Deficient Strain of Cryptococcus neoformans

by Rajendra Upadhya, Woei C. Lam, Brian Maybruck, Charles A. Specht, Stuart M. Levitz, Jennifer K. Lodge
Published 2016-05-01

Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis

by Rajendra Upadhya, Lorina G. Baker, Woei C. Lam, Charles A. Specht, Maureen J. Donlin, Jennifer K. Lodge
Published 2018-11-01

Functional specialization among members of Knickkopf family of proteins in insect cuticle organization.

by Sujata S Chaudhari, Bernard Moussian, Charles A Specht, Yasuyuki Arakane, Karl J Kramer, Richard W Beeman, Subbaratnam Muthukrishnan
Published 2014-08-01

Retroactive maintains cuticle integrity by promoting the trafficking of Knickkopf into the procuticle of Tribolium castaneum.

by Sujata S Chaudhari, Yasuyuki Arakane, Charles A Specht, Bernard Moussian, Karl J Kramer, Subbaratnam Muthukrishnan, Richard W Beeman
Published 2013-01-01

The Aminoalkylindole BML-190 Negatively Regulates Chitosan Synthesis via the Cyclic AMP/Protein Kinase A1 Pathway in Cryptococcus neoformans

by Brian T. Maybruck, Woei C. Lam, Charles A. Specht, Ma. Xenia G. Ilagan, Maureen J. Donlin, Jennifer K. Lodge
Published 2019-12-01

Pharyngeal polysaccharide deacetylases affect development in the nematode C. elegans and deacetylate chitin in vitro.

by Ronald J Heustis, Hong K Ng, Kenneth J Brand, Meredith C Rogers, Linda T Le, Charles A Specht, Juliet A Fuhrman
Published 2012-01-01

Chitosan Biosynthesis and Virulence in the Human Fungal Pathogen Cryptococcus gattii

by Woei C. Lam, Rajendra Upadhya, Charles A. Specht, Abigail E. Ragsdale, Camaron R. Hole, Stuart M. Levitz, Jennifer K. Lodge
Published 2019-10-01

Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma.

by Evelyn Santos Guerra, Chrono K Lee, Charles A Specht, Bhawna Yadav, Haibin Huang, Ali Akalin, Jun R Huh, Christian Mueller, Stuart M Levitz
Published 2017-01-01

Recognition of Aspergillus fumigatus hyphae by human plasmacytoid dendritic cells is mediated by dectin-2 and results in formation of extracellular traps.

by Flávio V Loures, Marc Röhm, Chrono K Lee, Evelyn Santos, Jennifer P Wang, Charles A Specht, Vera L G Calich, Constantin F Urban, Stuart M Levitz
Published 2015-02-01

Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.

by Darin L Wiesner, Charles A Specht, Chrono K Lee, Kyle D Smith, Liliane Mukaremera, S Thera Lee, Chun G Lee, Jack A Elias, Judith N Nielsen, David R Boulware, Paul R Bohjanen, Marc K Jenkins, Stuart M Levitz, Kirsten Nielsen
Published 2015-03-01

Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species

by Charles A. Specht, Chrono K. Lee, Haibin Huang, Maureen M. Hester, Jianhua Liu, Bridget A. Luckie, Melanie A. Torres Santana, Zeynep Mirza, Payam Khoshkenar, Ambily Abraham, Zu T. Shen, Jennifer K. Lodge, Ali Akalin, Jane Homan, Gary R. Ostroff, Stuart M. Levitz, Kirsten Nielsen
Published 2017-11-01

Structural basis of Blastomyces Endoglucanase-2 adjuvancy in anti-fungal and -viral immunity.

by Lucas Dos Santos Dias, Hannah E Dobson, Brock Kingstad Bakke, Gregory C Kujoth, Junfeng Huang, Elaine M Kohn, Cleison Ledesma Taira, Huafeng Wang, Nitin T Supekar, J Scott Fites, Daisy Gates, Christina L Gomez, Charles A Specht, Stuart M Levitz, Parastoo Azadi, Lingjun Li, Marulasiddappa Suresh, Bruce S Klein, Marcel Wüthrich
Published 2021-03-01