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Chan, J.C.Y
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Chan, J.C.Y
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Predicting human tissue exposures to xenobiotics using a bottom-up physiologically-based biokinetic model
by
Chan, E.C.Y
,
Chan
,
J.C.Y
,
Tan, S.P.F
Published 2021
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Related Subjects
Animals
Article
Drug Interactions
Humans
IC50
Liver
Models, Biological
Rosuvastatin Calcium
Xenobiotics
animal
bile canaliculus
biliary excretion
biological model
common hepatic duct
cyclosporine
drug bioavailability
drug interaction
gene expression
human
human tissue
liver
liver weight
maximum concentration
maximum plasma concentration
plasma concentration-time curve
positron emission tomography
prediction
risk assessment
rosuvastatin
sensitivity analysis
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