Reconciling isothermal titration calorimetry analyses of interactions between complexin and truncated SNARE complexes

by Eric A Prinslow, Chad A Brautigam, Josep Rizo
Published 2017-09-01

Multi-signal sedimentation velocity analysis with mass conservation for determining the stoichiometry of protein complexes.

by Chad A Brautigam, Shae B Padrick, Peter Schuck
Published 2013-01-01

S. aureus MscL is a pentamer in vivo but of variable stoichiometries in vitro: implications for detergent-solubilized membrane proteins.

by Michael R Dorwart, Robin Wray, Chad A Brautigam, Youxing Jiang, Paul Blount
Published 2010-12-01

Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin

by Yuxiao Wang, Heath G Pascoe, Chad A Brautigam, Huawei He, Xuewu Zhang
Published 2013-10-01

The Tp0684 (MglB-2) Lipoprotein of Treponema pallidum: A Glucose-Binding Protein with Divergent Topology.

by Chad A Brautigam, Ranjit K Deka, Wei Z Liu, Michael V Norgard
Published 2016-01-01

Structural determinants of nuclear export signal orientation in binding to exportin CRM1

by Ho Yee Joyce Fung, Szu-Chin Fu, Chad A Brautigam, Yuh Min Chook
Published 2015-09-01

Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex

by Guijun Shang, Chad A Brautigam, Rui Chen, Defen Lu, Jesús Torres-Vázquez, Xuewu Zhang
Published 2017-05-01

Design principles of a microtubule polymerase

by Elisabeth A Geyer, Matthew P Miller, Chad A Brautigam, Sue Biggins, Luke M Rice
Published 2018-06-01

SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK

by Sung Jun Bae, Lisheng Ni, Adam Osinski, Diana R Tomchick, Chad A Brautigam, Xuelian Luo
Published 2017-10-01

Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands

by Jie Li, Guijun Shang, Yu-Ju Chen, Chad A Brautigam, Jen Liou, Xuewu Zhang, Xiao-chen Bai
Published 2019-09-01

The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochores

by Sushama Sivakumar, Paweł Ł Janczyk, Qianhui Qu, Chad A Brautigam, P Todd Stukenberg, Hongtao Yu, Gary J Gorbsky
Published 2016-03-01

The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop

by Xu Zhang, Jiaxi Wu, Fenghe Du, Hui Xu, Lijun Sun, Zhe Chen, Chad A. Brautigam, Xuewu Zhang, Zhijian J. Chen
Published 2014-02-01

Autoinhibition of Munc18-1 modulates synaptobrevin binding and helps to enable Munc13-dependent regulation of membrane fusion

by Ewa Sitarska, Junjie Xu, Seungmee Park, Xiaoxia Liu, Bradley Quade, Karolina Stepien, Kyoko Sugita, Chad A Brautigam, Shuzo Sugita, Josep Rizo
Published 2017-05-01

Mechanism of karyopherin-β2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X)

by Abner Gonzalez, Taro Mannen, Tolga Çağatay, Ayano Fujiwara, Hiroyoshi Matsumura, Ashley B. Niesman, Chad A. Brautigam, Yuh Min Chook, Takuya Yoshizawa
Published 2021-02-01

Rac1 GTPase activates the WAVE regulatory complex through two distinct binding sites

by Baoyu Chen, Hui-Ting Chou, Chad A Brautigam, Wenmin Xing, Sheng Yang, Lisa Henry, Lynda K Doolittle, Thomas Walz, Michael K Rosen
Published 2017-09-01

Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing

by Melissa L. Brulotte, Byung-Cheon Jeong, Faxiang Li, Bing Li, Eric B. Yu, Qiong Wu, Chad A. Brautigam, Hongtao Yu, Xuelian Luo
Published 2017-12-01

Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7.

by Mingshan Xue, Timothy K Craig, Ok-Ho Shin, Liyi Li, Chad A Brautigam, Diana R Tomchick, Thomas C Südhof, Christian Rosenmund, Josep Rizo
Published 2010-09-01

Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone

by Abhilash Padavannil, Prithwijit Sarkar, Seung Joong Kim, Tolga Cagatay, Jenny Jiou, Chad A Brautigam, Diana R Tomchick, Andrej Sali, Sheena D'Arcy, Yuh Min Chook
Published 2019-03-01

A tethered delivery mechanism explains the catalytic action of a microtubule polymerase

by Pelin Ayaz, Sarah Munyoki, Elisabeth A Geyer, Felipe-Andrés Piedra, Emily S Vu, Raquel Bromberg, Zbyszek Otwinowski, Nick V Grishin, Chad A Brautigam, Luke M Rice
Published 2014-08-01

Structural basis of arrestin-3 activation and signaling

by Qiuyan Chen, Nicole A. Perry, Sergey A. Vishnivetskiy, Sandra Berndt, Nathaniel C. Gilbert, Ya Zhuo, Prashant K. Singh, Jonas Tholen, Melanie D. Ohi, Eugenia V. Gurevich, Chad A. Brautigam, Candice S. Klug, Vsevolod V. Gurevich, T. M. Iverson
Published 2017-11-01