Editorial for the Special Issue: “Targeting β-Lactamases to Fight Bacterial Resistance to β-Lactam Antibiotics”

by Cecilia Pozzi
Published 2020-05-01

Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS)

by Cecilia Pozzi, Ludovica Lopresti, Giusy Tassone, Stefano Mangani
Published 2019-04-01

Validation of Recombinant Chicken Liver Bile Acid Binding Protein as a Tool for Cholic Acid Hosting

by Giusy Tassone, Maurizio Orlandini, Massimo Olivucci, Cecilia Pozzi
Published 2021-04-01

Dynamic Interplay between Copper Toxicity and Mitochondrial Dysfunction in Alzheimer’s Disease

by Giusy Tassone, Arian Kola, Daniela Valensin, Cecilia Pozzi
Published 2021-04-01

Structural and Functional Characterization of the Human Thymidylate Synthase (hTS) Interface Variant R175C, New Perspectives for the Development of hTS Inhibitors

by Cecilia Pozzi, Stefania Ferrari, Rosaria Luciani, Maria Paola Costi, Stefano Mangani
Published 2019-04-01

Evidence of Destabilization of the Human Thymidylate Synthase (hTS) Dimeric Structure Induced by the Interface Mutation Q62R

by Cecilia Pozzi, Ludovica Lopresti, Matteo Santucci, Maria Paola Costi, Stefano Mangani
Published 2019-04-01

Elevación máxima del agua en la laguna Mar Chiquita, Córdoba, Argentina

by Mariana Pagot, Gerardo Hillman, Cecilia Pozzi-Piacenza, Paolo Gyssels, Antoine Patalano, Andrés Rodriguez
Published 2014-07-01

Structural Comparison of <i>Enterococcus faecalis</i> and Human Thymidylate Synthase Complexes with the Substrate dUMP and Its Analogue FdUMP Provides Hints about Enzyme Conformati...

by Cecilia Pozzi, Stefania Ferrari, Rosaria Luciani, Giusy Tassone, Maria Paola Costi, Stefano Mangani
Published 2019-03-01

In Silico Identification and In Vitro Evaluation of Natural Inhibitors of Leishmania major Pteridine Reductase I

by Fabian C. Herrmann, Nirina Sivakumar, Joachim Jose, Maria P. Costi, Cecilia Pozzi, Thomas J. Schmidt
Published 2017-12-01

Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of <i>Trypanosoma brucei</i> Pteridine Reductase and Dihydrofolate Reductase

by Giusy Tassone, Giacomo Landi, Pasquale Linciano, Valeria Francesconi, Michele Tonelli, Lorenzo Tagliazucchi, Maria Paola Costi, Stefano Mangani, Cecilia Pozzi
Published 2021-06-01

Small Molecules as Potential Inhibitors of the 14-3-3/c-Abl Interaction for the Treatment of CML

by Leire Iralde-Lorente, Giusy Tassone, Ylenia Cau, Claire Munier, Lorenzo Franci, Cecilia Pozzi, Adriano Angelucci, Mario Chiariello, Matthew Perry, Stefano Mangani, Maurizio Botta
Published 2019-08-01

Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations

by Cecilia Pozzi, Matteo Santucci, Gaetano Marverti, Domenico D’Arca, Lorenzo Tagliazucchi, Stefania Ferrari, Gaia Gozzi, Lorena Losi, Giusy Tassone, Stefano Mangani, Glauco Ponterini, Maria Paola Costi
Published 2021-04-01

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery

by Pasquale Linciano, Alice Dawson, Ina Pöhner, David M. Costa, Monica S. Sá, Anabela Cordeiro-da-Silva, Rosaria Luciani, Sheraz Gul, Gesa Witt, Bernhard Ellinger, Maria Kuzikov, Philip Gribbon, Jeanette Reinshagen, Markus Wolf, Birte Behrens, Véronique Hannaert, Paul A. M. Michels, Erika Nerini, Cecilia Pozzi, Flavio di Pisa, Giacomo Landi, Nuno Santarem, Stefania Ferrari, Puneet Saxena, Sandra Lazzari, Giuseppe Cannazza, Lucio H. Freitas-Junior, Carolina B. Moraes, Bruno S. Pascoalino, Laura M. Alcântara, Claudia P. Bertolacini, Vanessa Fontana, Ulrike Wittig, Wolfgang Müller, Rebecca C. Wade, William N. Hunter, Stefano Mangani, Luca Costantino, Maria P. Costi
Published 2017-09-01