Mutation in E1, the ubiquitin activating enzyme, reduces Drosophila lifespan and results in motor impairment.

by Hsiu-Yu Liu, Cathie M Pfleger
Published 2013-01-01

The Hippo Pathway Targets Rae1 to Regulate Mitosis and Organ Size and to Feed Back to Regulate Upstream Components Merlin, Hippo, and Warts.

by Maryam Jahanshahi, Kuangfu Hsiao, Andreas Jenny, Cathie M Pfleger
Published 2016-08-01

Alcohol interacts with genetic alteration of the Hippo tumor suppressor pathway to modulate tissue growth in Drosophila.

by Anoj Ilanges, Maryam Jahanshahi, Denis M Balobin, Cathie M Pfleger
Published 2013-01-01

Grape-Seed Polyphenolic Extract Improves the Eye Phenotype in a Drosophila Model of Tauopathy

by Cathie M. Pfleger, Jun Wang, Lauren Friedman, Roselle Vittorino, Lindsay M. Conley, Lap Ho, Hayley C. Fivecoat, Giulio M. Pasinetti
Published 2010-01-01

A conserved, N-terminal tyrosine signal directs Ras for inhibition by Rabex-5.

by Chalita Washington, Rachel Chernet, Rewatee H Gokhale, Yesenia Martino-Cortez, Hsiu-Yu Liu, Ashley M Rosenberg, Sivan Shahar, Cathie M Pfleger
Published 2020-06-01