La investigación oncológica en España

by Carlos López Otín
Published 2001-02-01

Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells

by Dido Carrero, Clara Soria-Valles, Carlos López-Otín
Published 2016-07-01

Estimation of copy number alterations from exome sequencing data.

by Rafael Valdés-Mas, Silvia Bea, Diana A Puente, Carlos López-Otín, Xose S Puente
Published 2012-01-01

Global Proteome of <i>LonP1</i>^+/− Mouse Embryonal Fibroblasts Reveals Impact on Respiratory Chain, but No Interdependence between Eral1 and Mitoribosomes

by Jana Key, Aneesha Kohli, Clea Bárcena, Carlos López-Otín, Juliana Heidler, Ilka Wittig, Georg Auburger
Published 2019-09-01

Matriptase-2 deficiency protects from obesity by modulating iron homeostasis

by Alicia R. Folgueras, Sandra Freitas-Rodríguez, Andrew J. Ramsay, Cecilia Garabaya, Francisco Rodríguez, Gloria Velasco, Carlos López-Otín
Published 2018-04-01

Functional interaction between acyl-CoA synthetase 4, lipooxygenases and cyclooxygenase-2 in the aggressive phenotype of breast cancer cells.

by Paula M Maloberti, Alejandra B Duarte, Ulises D Orlando, María E Pasqualini, Angela R Solano, Carlos López-Otín, Ernesto J Podestá
Published 2010-01-01

LPS responsiveness and neutrophil chemotaxis in vivo require PMN MMP-8 activity.

by Angus M Tester, Jennifer H Cox, Andrea R Connor, Amanda E Starr, Richard A Dean, Xose S Puente, Carlos López-Otín, Christopher M Overall
Published 2007-01-01

Arresten, a collagen-derived angiogenesis inhibitor, suppresses invasion of squamous cell carcinoma.

by Mari Aikio, Ilkka Alahuhta, Sini Nurmenniemi, Juho Suojanen, Riitta Palovuori, Susanna Teppo, Timo Sorsa, Carlos López-Otín, Taina Pihlajaniemi, Tuula Salo, Ritva Heljasvaara, Pia Nyberg
Published 2012-01-01

Progerin accelerates atherosclerosis by inducing endoplasmic reticulum stress in vascular smooth muscle cells

by Magda R Hamczyk, Ricardo Villa‐Bellosta, Víctor Quesada, Pilar Gonzalo, Sandra Vidak, Rosa M Nevado, María J Andrés‐Manzano, Tom Misteli, Carlos López‐Otín, Vicente Andrés
Published 2019-04-01

Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10.

by Emilio García-Prieto, Adrián González-López, Sandra Cabrera, Aurora Astudillo, Ana Gutiérrez-Fernández, Miriam Fanjul-Fernandez, Estefanía Batalla-Solís, Xose S Puente, Antonio Fueyo, Carlos López-Otín, Guillermo M Albaiceta
Published 2010-01-01

ATP-Dependent Lon Protease Controls Tumor Bioenergetics by Reprogramming Mitochondrial Activity

by Pedro M. Quirós, Yaiza Español, Rebeca Acín-Pérez, Francisco Rodríguez, Clea Bárcena, Kenta Watanabe, Enrique Calvo, Marta Loureiro, M. Soledad Fernández-García, Antonio Fueyo, Jesús Vázquez, José Antonio Enríquez, Carlos López-Otín
Published 2014-07-01

Correction: Regulation of ATG4B Stability by RNF5 Limits Basal Levels of Autophagy and Influences Susceptibility to Bacterial Infection.

by Ersheng Kuang, Cheryl Y M Okumura, Sharon Sheffy-Levin, Tal Varsano, Vincent Chih-Wen Shu, Jianfei Qi, Ingrid R Niesman, Huei-Jiun Yang, Carlos López-Otín, Wei Yuan Yang, John C Reed, Limor Broday, Victor Nizet, Ze'ev A Ronai
Published 2020-05-01

Regulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection.

by Ersheng Kuang, Cheryl Y M Okumura, Sharon Sheffy-Levin, Tal Varsano, Vincent Chih-Wen Shu, Jianfei Qi, Ingrid R Niesman, Huei-Jiun Yang, Carlos López-Otín, Wei Yuan Yang, John C Reed, Limor Broday, Victor Nizet, Ze'ev A Ronai
Published 2012-01-01

Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics

by Helen E. Speedy, Renée Beekman, Vicente Chapaprieta, Giulia Orlando, Philip J. Law, David Martín-García, Jesús Gutiérrez-Abril, Daniel Catovsky, Sílvia Beà, Guillem Clot, Montserrat Puiggròs, David Torrents, Xose S. Puente, James M. Allan, Carlos López-Otín, Elias Campo, Richard S. Houlston, José I. Martín-Subero
Published 2019-08-01

Genetic Predisposition to Chronic Lymphocytic Leukemia Is Mediated by a BMF Super-Enhancer Polymorphism

by Radhika Kandaswamy, Georgina P. Sava, Helen E. Speedy, Sílvia Beà, José I. Martín-Subero, James B. Studd, Gabriele Migliorini, Philip J. Law, Xose S. Puente, David Martín-García, Itziar Salaverria, Jesús Gutiérrez-Abril, Carlos López-Otín, Daniel Catovsky, James M. Allan, Elías Campo, Richard S. Houlston
Published 2016-08-01

The microRNA-29/PGC1α regulatory axis is critical for metabolic control of cardiac function.

by Xurde M Caravia, Víctor Fanjul, Eduardo Oliver, David Roiz-Valle, Alba Morán-Álvarez, Gabriela Desdín-Micó, María Mittelbrunn, Roberto Cabo, José A Vega, Francisco Rodríguez, Antonio Fueyo, Mónica Gómez, Manuel Lobo-González, Héctor Bueno, Gloria Velasco, José M P Freije, Vicente Andrés, Borja Ibáñez, Alejandro P Ugalde, Carlos López-Otín
Published 2018-10-01

Insights into the Evolution of Longevity from the Bowhead Whale Genome

by Michael Keane, Jeremy Semeiks, Andrew E. Webb, Yang I. Li, Víctor Quesada, Thomas Craig, Lone Bruhn Madsen, Sipko van Dam, David Brawand, Patrícia I. Marques, Pawel Michalak, Lin Kang, Jong Bhak, Hyung-Soon Yim, Nick V. Grishin, Nynne Hjort Nielsen, Mads Peter Heide-Jørgensen, Elias M. Oziolor, Cole W. Matson, George M. Church, Gary W. Stuart, John C. Patton, J. Craig George, Robert Suydam, Knud Larsen, Carlos López-Otín, Mary J. O’Connell, John W. Bickham, Bo Thomsen, João Pedro de Magalhães
Published 2015-01-01

A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features

by Kaustubh Adhikari, Tania Fontanil, Santiago Cal, Javier Mendoza-Revilla, Macarena Fuentes-Guajardo, Juan-Camilo Chacón-Duque, Farah Al-Saadi, Jeanette A. Johansson, Mirsha Quinto-Sanchez, Victor Acuña-Alonzo, Claudia Jaramillo, William Arias, Rodrigo Barquera Lozano, Gastón Macín Pérez, Jorge Gómez-Valdés, Hugo Villamil-Ramírez, Tábita Hunemeier, Virginia Ramallo, Caio C. Silva de Cerqueira, Malena Hurtado, Valeria Villegas, Vanessa Granja, Carla Gallo, Giovanni Poletti, Lavinia Schuler-Faccini, Francisco M. Salzano, Maria-Cátira Bortolini, Samuel Canizales-Quinteros, Francisco Rothhammer, Gabriel Bedoya, Rolando Gonzalez-José, Denis Headon, Carlos López-Otín, Desmond J. Tobin, David Balding, Andrés Ruiz-Linares
Published 2016-03-01