Efficacy of ARV-1502, a Proline-Rich Antimicrobial Peptide, in a Murine Model of Bacteremia Caused by Multi-Drug Resistant (MDR) <i>Acinetobacter baumannii</i>

by Yan Q. Xiong, Liang Li, Yufeng Zhou, Carl N. Kraus
Published 2019-08-01

Quantitation of a Novel Engineered Anti-infective Host Defense Peptide, ARV-1502: Pharmacokinetic Study of Different Doses in Rats and Dogs

by Alexandra Brakel, Alexandra Brakel, Daniela Volke, Daniela Volke, Carl N. Kraus, Laszlo Otvos, Laszlo Otvos, Ralf Hoffmann, Ralf Hoffmann
Published 2019-11-01

Advantage of a Narrow Spectrum Host Defense (Antimicrobial) Peptide Over a Broad Spectrum Analog in Preclinical Drug Development

by Eszter Ostorhazi, Ralf Hoffmann, Nicole Herth, John D. Wade, John D. Wade, Carl N. Kraus, Laszlo Otvos Jr., Laszlo Otvos Jr., Laszlo Otvos Jr.
Published 2018-08-01

Synergy Between Proline-Rich Antimicrobial Peptides and Small Molecule Antibiotics Against Selected Gram-Negative Pathogens in vitro and in vivo

by Laszlo Otvos Jr., Laszlo Otvos Jr., Laszlo Otvos Jr., Eszter Ostorhazi, Dora Szabo, Steven D. Zumbrun, Lynda L. Miller, Stephanie A. Halasohoris, Puvi D. Desai, Sharon M. Int Veldt, Carl N. Kraus
Published 2018-08-01