Mechanistic Models of Signaling Pathways Reveal the Drug Action Mechanisms behind Gender-Specific Gene Expression for Cancer Treatments

by Cankut Çubuk, Fatma E. Can, María Peña-Chilet, Joaquín Dopazo
Published 2020-06-01

Models of cell signaling uncover molecular mechanisms of high-risk neuroblastoma and predict disease outcome

by Marta R. Hidalgo, Alicia Amadoz, Cankut Çubuk, José Carbonell-Caballero, Joaquín Dopazo
Published 2018-08-01

Genome-scale mechanistic modeling of signaling pathways made easy: A bioconductor/cytoscape/web server framework for the analysis of omic data

by Kinza Rian, Marta R. Hidalgo, Cankut Çubuk, Matias M. Falco, Carlos Loucera, Marina Esteban-Medina, Inmaculada Alamo-Alvarez, María Peña-Chilet, Joaquín Dopazo
Published 2021-01-01

Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity

by Kasparas Petkevicius, Sam Virtue, Guillaume Bidault, Benjamin Jenkins, Cankut Çubuk, Cecilia Morgantini, Myriam Aouadi, Joaquin Dopazo, Mireille J Serlie, Albert Koulman, Antonio Vidal-Puig
Published 2019-08-01

Mechanistic modeling of the SARS-CoV-2 disease map

by Kinza Rian, Marina Esteban-Medina, Marta R. Hidalgo, Cankut Çubuk, Matias M. Falco, Carlos Loucera, Devrim Gunyel, Marek Ostaszewski, María Peña-Chilet, Joaquín Dopazo
Published 2021-01-01

Stress-induced activation of brown adipose tissue prevents obesity in conditions of low adaptive thermogenesis

by Maria Razzoli, Andrea Frontini, Allison Gurney, Eleonora Mondini, Cankut Cubuk, Liora S. Katz, Cheryl Cero, Patrick J. Bolan, Joaquin Dopazo, Antonio Vidal-Puig, Saverio Cinti, Alessandro Bartolomucci
Published 2016-01-01

The effects of death and post-mortem cold ischemia on human tissue transcriptomes

by Pedro G. Ferreira, Manuel Muñoz-Aguirre, Ferran Reverter, Caio P. Sá Godinho, Abel Sousa, Alicia Amadoz, Reza Sodaei, Marta R. Hidalgo, Dmitri Pervouchine, Jose Carbonell-Caballero, Ramil Nurtdinov, Alessandra Breschi, Raziel Amador, Patrícia Oliveira, Cankut Çubuk, João Curado, François Aguet, Carla Oliveira, Joaquin Dopazo, Michael Sammeth, Kristin G. Ardlie, Roderic Guigó
Published 2018-02-01

Taxonomic variations in the gut microbiome of gout patients with and without tophi might have a functional impact on urate metabolism

by Eder Orlando Méndez-Salazar, Janitzia Vázquez-Mellado, Carlos S. Casimiro-Soriguer, Joaquin Dopazo, Cankut Çubuk, Yessica Zamudio-Cuevas, Adriana Francisco-Balderas, Karina Martínez-Flores, Javier Fernández-Torres, Carlos Lozada-Pérez, Carlos Pineda, Austreberto Sánchez-González, Luis H. Silveira, Ana I. Burguete-García, Citlalli Orbe-Orihuela, Alfredo Lagunas-Martínez, Alonso Vazquez-Gomez, Alberto López-Reyes, Berenice Palacios-González, Gabriela Angélica Martínez-Nava
Published 2021-05-01