Obtaining consent for future research with induced pluripotent cells: opportunities and challenges.

by Katriina Aalto-Setälä, Bruce R Conklin, Bernard Lo
Published 2009-02-01

Finding the right questions: exploratory pathway analysis to enhance biological discovery in large datasets.

by Thomas Kelder, Bruce R Conklin, Chris T Evelo, Alexander R Pico
Published 2010-08-01

Engineering the melanocortin-4 receptor to control constitutive and ligand-mediated G(S) signaling in vivo.

by Supriya Srinivasan, Pamela Santiago, Cecile Lubrano, Christian Vaisse, Bruce R Conklin
Published 2007-08-01

G(i)-coupled GPCR signaling controls the formation and organization of human pluripotent colonies.

by Kenta Nakamura, Nathan Salomonis, Kiichiro Tomoda, Shinya Yamanaka, Bruce R Conklin
Published 2009-11-01

Allele-Specific Gene Editing Rescues Pathology in a Human Model of Charcot-Marie-Tooth Disease Type 2E

by Carissa M. Feliciano, Carissa M. Feliciano, Kenneth Wu, Hannah L. Watry, Chiara B. E. Marley, Chiara B. E. Marley, Gokul N. Ramadoss, Gokul N. Ramadoss, Hana Y. Ghanim, Angela Z. Liu, Angela Z. Liu, Lyandysha V. Zholudeva, Todd C. McDevitt, Todd C. McDevitt, Mario A. Saporta, Bruce R. Conklin, Bruce R. Conklin, Bruce R. Conklin, Bruce R. Conklin, Luke M. Judge, Luke M. Judge
Published 2021-08-01

AlleleAnalyzer: a tool for personalized and allele-specific sgRNA design

by Kathleen C. Keough, Svetlana Lyalina, Michael P. Olvera, Sean Whalen, Bruce R. Conklin, Katherine S. Pollard
Published 2019-08-01

WikiPathways: pathway editing for the people.

by Alexander R Pico, Thomas Kelder, Martijn P van Iersel, Kristina Hanspers, Bruce R Conklin, Chris Evelo
Published 2008-07-01

Mining biological pathways using WikiPathways web services.

by Thomas Kelder, Alexander R Pico, Kristina Hanspers, Martijn P van Iersel, Chris Evelo, Bruce R Conklin
Published 2009-07-01

Modifying ligand-induced and constitutive signaling of the human 5-HT4 receptor.

by Wei Chun Chang, Jennifer K Ng, Trieu Nguyen, Lucie Pellissier, Sylvie Claeysen, Edward C Hsiao, Bruce R Conklin
Published 2007-12-01

A Non-invasive Platform for Functional Characterization of Stem-Cell-Derived Cardiomyocytes with Applications in Cardiotoxicity Testing

by Mahnaz Maddah, Julia D. Heidmann, Mohammad A. Mandegar, Chase D. Walker, Sara Bolouki, Bruce R. Conklin, Kevin E. Loewke
Published 2015-04-01

Critical Roles of Translation Initiation and RNA Uridylation in Endogenous Retroviral Expression and Neural Differentiation in Pluripotent Stem Cells

by Kazutoshi Takahashi, Daeun Jeong, Songnan Wang, Megumi Narita, Xuemei Jin, Mio Iwasaki, Samuel D. Perli, Bruce R. Conklin, Shinya Yamanaka
Published 2020-06-01

Alternative splicing in the differentiation of human embryonic stem cells into cardiac precursors.

by Nathan Salomonis, Brandon Nelson, Karen Vranizan, Alexander R Pico, Kristina Hanspers, Allan Kuchinsky, Linda Ta, Mark Mercola, Bruce R Conklin
Published 2009-11-01

Transcription factor overexpression drives reliable differentiation of retinal pigment epithelium from human induced pluripotent stem cells

by Tessa E. Dewell, Ketrin Gjoni, Angela Z. Liu, Ashley R.G. Libby, Anthony T. Moore, Po-Lin So, Bruce R. Conklin
Published 2021-05-01

Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity

by Duy P. Nguyen, Yuichiro Miyaoka, Luke A. Gilbert, Steven J. Mayerl, Brian H. Lee, Jonathan S. Weissman, Bruce R. Conklin, James A. Wells
Published 2016-07-01

AKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to β-adrenergic-induced cardiac hypertrophy.

by Matthew J Spindler, Brian T Burmeister, Yu Huang, Edward C Hsiao, Nathan Salomonis, Mark J Scott, Deepak Srivastava, Graeme K Carnegie, Bruce R Conklin
Published 2013-01-01

Marking embryonic stem cells with a 2A self-cleaving peptide: a NKX2-5 emerald GFP BAC reporter.

by Edward C Hsiao, Yuko Yoshinaga, Trieu D Nguyen, Stacy L Musone, Judy E Kim, Paul Swinton, Isidro Espineda, Carlota Manalac, Pieter J deJong, Bruce R Conklin
Published 2008-07-01

Spatiotemporal mosaic self-patterning of pluripotent stem cells using CRISPR interference

by Ashley RG Libby, David A Joy, Po-Lin So, Mohammad A Mandegar, Jonathon M Muncie, Federico N Mendoza-Camacho, Valerie M Weaver, Bruce R Conklin, Todd C McDevitt
Published 2018-10-01

Phenotype-Based High-Throughput Classification of Long QT Syndrome Subtypes Using Human Induced Pluripotent Stem Cells

by Daisuke Yoshinaga, Shiro Baba, Takeru Makiyama, Hirofumi Shibata, Takuya Hirata, Kentaro Akagi, Koichi Matsuda, Hirohiko Kohjitani, Yimin Wuriyanghai, Katsutsugu Umeda, Yuta Yamamoto, Bruce R. Conklin, Minoru Horie, Junko Takita, Toshio Heike
Published 2019-08-01

Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture

by Anna L. Lahti, Ville J. Kujala, Hugh Chapman, Ari-Pekka Koivisto, Mari Pekkanen-Mattila, Erja Kerkelä, Jari Hyttinen, Kimmo Kontula, Heikki Swan, Bruce R. Conklin, Shinya Yamanaka, Olli Silvennoinen, Katriina Aalto-Setälä
Published 2012-03-01

Modeling insertional mutagenesis using gene length and expression in murine embryonic stem cells.

by Alex S Nord, Karen Vranizan, Whittemore Tingley, Alexander C Zambon, Kristina Hanspers, Loren G Fong, Yan Hu, Peter Bacchetti, Thomas E Ferrin, Patricia C Babbitt, Scott W Doniger, William C Skarnes, Stephen G Young, Bruce R Conklin
Published 2007-07-01