Roles of the HUWE1 ubiquitin ligase in nervous system development, function and disease

by Andrew C. Giles, Brock Grill
Published 2020-04-01

Synapse maintenance is impacted by ATAT-2 tubulin acetyltransferase activity and the RPM-1 signaling hub

by Melissa A Borgen, Andrew C Giles, Dandan Wang, Brock Grill
Published 2019-01-01

The Nesprin family member ANC-1 regulates synapse formation and axon termination by functioning in a pathway with RPM-1 and β-Catenin.

by Erik D Tulgren, Shane M Turgeon, Karla J Opperman, Brock Grill
Published 2014-07-01

Modulating Behavior in C. elegans Using Electroshock and Antiepileptic Drugs.

by Monica G Risley, Stephanie P Kelly, Kailiang Jia, Brock Grill, Ken Dawson-Scully
Published 2016-01-01

A MIG-15/JNK-1 MAP kinase cascade opposes RPM-1 signaling in synapse formation and learning.

by Oliver Crawley, Andrew C Giles, Muriel Desbois, Sudhanva Kashyap, Rayna Birnbaum, Brock Grill
Published 2017-12-01

RPM-1 uses both ubiquitin ligase and phosphatase-based mechanisms to regulate DLK-1 during neuronal development.

by Scott T Baker, Karla J Opperman, Erik D Tulgren, Shane M Turgeon, Willy Bienvenut, Brock Grill
Published 2014-05-01

Autophagy is inhibited by ubiquitin ligase activity in the nervous system

by Oliver Crawley, Karla J. Opperman, Muriel Desbois, Isabel Adrados, Melissa A. Borgen, Andrew C. Giles, Derek R. Duckett, Brock Grill
Published 2019-11-01

The HECT Family Ubiquitin Ligase EEL-1 Regulates Neuronal Function and Development

by Karla J. Opperman, Ben Mulcahy, Andrew C. Giles, Monica G. Risley, Rayna L. Birnbaum, Erik D. Tulgren, Ken Dawson-Scully, Mei Zhen, Brock Grill
Published 2017-04-01

An alternatively spliced, non-signaling insulin receptor modulates insulin sensitivity via insulin peptide sequestration in C. elegans

by Bryan A Martinez, Pedro Reis Rodrigues, Ricardo M Nuñez Medina, Prosenjit Mondal, Neale J Harrison, Museer A Lone, Amanda Webster, Aditi U Gurkar, Brock Grill, Matthew S Gill
Published 2020-02-01