DNA Vaccines: Recent Developments and the Future

by Britta Wahren, Margaret A. Liu
Published 2014-10-01

Intracellular Targeting of CEA Results in Th1-Type Antibody Responses Following Intradermal Genetic Vaccination by a Needle-Free Jet Injection Device

by Susanne Johansson, Monica Ek, Britta Wahren, Richard Stout, Margaret A. Liu, Kristian Hallermalm
Published 2007-01-01

Correction: DNA immunization site determines the level of gene expression and the magnitude, but not the type of the induced immune response.

by Stefan Petkov, Elizaveta Starodubova, Anastasia Latanova, Athina Kilpeläinen, Oleg Latyshev, Simons Svirskis, Britta Wahren, Francesca Chiodi, Ilya Gordeychuk, Maria Isaguliants
Published 2021-01-01

Skin electroporation: effects on transgene expression, DNA persistence and local tissue environment.

by Anna-Karin Roos, Fredrik Eriksson, James A Timmons, Josefine Gerhardt, Ulrika Nyman, Lindvi Gudmundsdotter, Andreas Bråve, Britta Wahren, Pavel Pisa
Published 2009-01-01

DNA immunization site determines the level of gene expression and the magnitude, but not the type of the induced immune response.

by Stefan Petkov, Elizaveta Starodubova, Anastasia Latanova, Athina Kilpeläinen, Oleg Latyshev, Simons Svirskis, Britta Wahren, Francesca Chiodi, Ilya Gordeychuk, Maria Isaguliants
Published 2018-01-01

A novel class of anti-HIV agents with multiple copies of enfuvirtide enhances inhibition of viral replication and cellular transmission in vitro.

by Chien-Hsing Chang, Jorma Hinkula, Meiyu Loo, Tina Falkeborn, Rongxiu Li, Thomas M Cardillo, Edmund A Rossi, David M Goldenberg, Britta Wahren
Published 2012-01-01

HIV-DNA Given with or without Intradermal Electroporation Is Safe and Highly Immunogenic in Healthy Swedish HIV-1 DNA/MVA Vaccinees: A Phase I Randomized Trial.

by Charlotta Nilsson, Bo Hejdeman, Karina Godoy-Ramirez, Teghesti Tecleab, Gabriella Scarlatti, Andreas Bråve, Patricia L Earl, Richard R Stout, Merlin L Robb, Robin J Shattock, Gunnel Biberfeld, Eric Sandström, Britta Wahren
Published 2015-01-01

Micro-minicircle Gene Therapy: Implications of Size on Fermentation, Complexation, Shearing Resistance, and Expression

by Sofia Stenler, Oscar PB Wiklander, Maria Badal-Tejedor, Janne Turunen, Joel Z Nordin, David Hallengärd, Britta Wahren, Samir EL Andaloussi, Mark W Rutland, CI Edvard Smith, Karin E Lundin, Pontus Blomberg
Published 2014-01-01

Frequent and Durable Anti-HIV Envelope VIV2 IgG Responses Induced by HIV-1 DNA Priming and HIV-MVA Boosting in Healthy Tanzanian Volunteers

by Agricola Joachim, Frank Msafiri, Sayali Onkar, Patricia Munseri, Said Aboud, Eligius F. Lyamuya, Muhammad Bakari, Erik Billings, Merlin L. Robb, Britta Wahren, Fred S. Mhalu, Eric Sandström, Mangala Rao, Charlotta Nilsson, Gunnel Biberfeld
Published 2020-11-01

Therapeutic DNA vaccination of vertically HIV-infected children: report of the first pediatric randomised trial (PEDVAC).

by Paolo Palma, Maria Luisa Romiti, Carla Montesano, Veronica Santilli, Nadia Mora, Angela Aquilani, Stefania Dispinseri, Hyppolite K Tchidjou, Marco Montano, Lars E Eriksson, Stefania Baldassari, Stefania Bernardi, Gabriella Scarlatti, Britta Wahren, Paolo Rossi
Published 2013-01-01

Potent functional antibody responses elicited by HIV-I DNA priming and boosting with heterologous HIV-1 recombinant MVA in healthy Tanzanian adults.

by Agricola Joachim, Charlotta Nilsson, Said Aboud, Muhammad Bakari, Eligius F Lyamuya, Merlin L Robb, Mary A Marovich, Patricia Earl, Bernard Moss, Christina Ochsenbauer, Britta Wahren, Fred Mhalu, Eric Sandström, Gunnel Biberfeld, Guido Ferrari, Victoria R Polonis
Published 2015-01-01

Immunotherapy with an HIV-DNA Vaccine in Children and Adults

by Paolo Palma, Lindvi Gudmundsdotter, Andrea Finocchi, Lars E. Eriksson, Nadia Mora, Veronica Santilli, Angela Aquilani, Emma C. Manno, Paola Zangari, Maria Luisa Romiti, Carla Montesano, Alba Grifoni, Andreas Brave, Karl Ljungberg, Pontus Blomberg, Stefania Bernardi, Eric Sandström, Bo Hejdeman, Paolo Rossi, Britta Wahren
Published 2014-07-01

Cellular Immune Response Induced by DNA Immunization of Mice with Drug Resistant Integrases of HIV-1 Clade A Offers Partial Protection against Growth and Metastatic Activity of Int...

by Maria Isaguliants, Olga Krotova, Stefan Petkov, Juris Jansons, Ekaterina Bayurova, Dzeina Mezale, Ilze Fridrihsone, Athina Kilpelainen, Philip Podschwadt, Yulia Agapkina, Olga Smirnova, Linda Kostic, Mina Saleem, Oleg Latyshev, Olesja Eliseeva, Anastasia Malkova, Tatiana Gorodnicheva, Britta Wahren, Ilya Gordeychuk, Elizaveta Starodubova, Anastasia Latanova
Published 2021-06-01

Boosting with Subtype C CN54rgp140 Protein Adjuvanted with Glucopyranosyl Lipid Adjuvant after Priming with HIV-DNA and HIV-MVA Is Safe and Enhances Immune Responses: A Phase I Tri...

by Agricola Joachim, Asli Bauer, Sarah Joseph, Christof Geldmacher, Patricia J Munseri, Said Aboud, Marco Missanga, Philipp Mann, Britta Wahren, Guido Ferrari, Victoria R Polonis, Merlin L Robb, Jonathan Weber, Roger Tatoud, Leonard Maboko, Michael Hoelscher, Eligius F Lyamuya, Gunnel Biberfeld, Eric Sandström, Arne Kroidl, Muhammad Bakari, Charlotta Nilsson, Sheena McCormack
Published 2016-01-01

Frequent Anti-V1V2 Responses Induced by HIV-DNA Followed by HIV-MVA with or without CN54rgp140/GLA-AF in Healthy African Volunteers

by Frank Msafiri, Agricola Joachim, Kathrin Held, Yuka Nadai, Raquel Matavele Chissumba, Christof Geldmacher, Said Aboud, Wolfgang Stöhr, Edna Viegas, Arne Kroidl, Muhammad Bakari, Patricia J. Munseri, Britta Wahren, Eric Sandström, Merlin L. Robb, Sheena McCormack, Sarah Joseph, Ilesh Jani, Guido Ferrari, Mangala Rao, Gunnel Biberfeld, Eligius Lyamuya, Charlotta Nilsson
Published 2020-11-01

Induction of Identical IgG HIV-1 Envelope Epitope Recognition Patterns After Initial HIVIS-DNA/MVA-CMDR Immunization and a Late MVA-CMDR Boost

by Agricola Joachim, Mohamed I. M. Ahmed, Mohamed I. M. Ahmed, Georgios Pollakis, Georgios Pollakis, Lisa Rogers, Lisa Rogers, Verena S. Hoffmann, Verena S. Hoffmann, Patricia Munseri, Said Aboud, Eligius F. Lyamuya, Muhammad Bakari, Merlin L. Robb, Merlin L. Robb, Britta Wahren, Eric Sandstrom, Charlotta Nilsson, Charlotta Nilsson, Gunnel Biberfeld, Christof Geldmacher, Christof Geldmacher, Kathrin Held, Kathrin Held
Published 2020-04-01

Priming with a simplified intradermal HIV-1 DNA vaccine regimen followed by boosting with recombinant HIV-1 MVA vaccine is safe and immunogenic: a phase IIa randomized clinical tri...

by Patricia J Munseri, Arne Kroidl, Charlotta Nilsson, Agricola Joachim, Christof Geldmacher, Philipp Mann, Candida Moshiro, Said Aboud, Eligius Lyamuya, Leonard Maboko, Marco Missanga, Bahati Kaluwa, Sayoki Mfinanga, Lilly Podola, Asli Bauer, Karina Godoy-Ramirez, Mary Marovich, Bernard Moss, Michael Hoelscher, Frances Gotch, Wolfgang Stöhr, Richard Stout, Sheena McCormack, Britta Wahren, Fred Mhalu, Merlin L Robb, Gunnel Biberfeld, Eric Sandström, Muhammad Bakari
Published 2015-01-01

Optimizing the immunogenicity of HIV prime-boost DNA-MVA-rgp140/GLA vaccines in a phase II randomized factorial trial design.

by Edna O Viegas, Arne Kroidl, Patricia J Munseri, Marco Missanga, Charlotta Nilsson, Nelson Tembe, Asli Bauer, Agricola Joachim, Sarah Joseph, Philipp Mann, Christof Geldmacher, Sue Fleck, Wolfgang Stöhr, Gabriella Scarlatti, Said Aboud, Muhammad Bakari, Leonard Maboko, Michael Hoelscher, Britta Wahren, Merlin L Robb, Jonathan Weber, Sheena McCormack, Gunnel Biberfeld, Ilesh V Jani, Eric Sandström, Eligius Lyamuya, TaMoVac study group
Published 2018-01-01