Bortezomib Warhead-Switch Confers Dual Activity against Mycobacterial Caseinolytic Protease and Proteasome and Selectivity against Human Proteasome

by Thomas Dick, Thomas Dick, Wilfried Moreira, Sridhar Santhanakrishnan, Brian W. Dymock
Published 2017-04-01

Intracellular Hyper-Acidification Potentiated by Hydrogen Sulfide Mediates Invasive and Therapy Resistant Cancer Cell Death

by Zheng-Wei Lee, Xin-Yi Teo, Zhi J. Song, Dawn S. Nin, Dawn S. Nin, Wisna Novera, Bok A. Choo, Bok A. Choo, Brian W. Dymock, Brian W. Dymock, Philip K. Moore, Philip K. Moore, Ruby Y.-J. Huang, Ruby Y.-J. Huang, Ruby Y.-J. Huang, Lih-Wen Deng, Lih-Wen Deng, Lih-Wen Deng
Published 2017-10-01

Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality

by Mayumi Kitagawa, Pei-Ju Liao, Kyung Hee Lee, Jasmine Wong, See Cheng Shang, Noriaki Minami, Oltea Sampetrean, Hideyuki Saya, Dai Lingyun, Nayana Prabhu, Go Ka Diam, Radoslaw Sobota, Andreas Larsson, Pär Nordlund, Frank McCormick, Sujoy Ghosh, David M. Epstein, Brian W. Dymock, Sang Hyun Lee
Published 2017-12-01