Regulation of Signaling and Metabolism by Lipin-mediated Phosphatidic Acid Phosphohydrolase Activity

by Andrew J. Lutkewitte, Brian N. Finck
Published 2020-09-01

Treating Hepatic Steatosis and Fibrosis by Modulating Mitochondrial Pyruvate MetabolismSummary

by Kyle S. McCommis, Brian N. Finck
Published 2019-01-01

Does Diacylglycerol Accumulation in Fatty Liver Disease Cause Hepatic Insulin Resistance?

by Brian N. Finck, Angela M. Hall
Published 2015-01-01

PPARs/RXRs in Cardiovascular Physiology and Disease

by Brian N. Finck, Giulia Chinetti, Bart Staels
Published 2008-01-01

Complex interplay between the lipin 1 and the hepatocyte nuclear factor 4 α (HNF4α) pathways to regulate liver lipid metabolism.

by Zhouji Chen, Matthew C Gropler, Mayurranjan S Mitra, Brian N Finck
Published 2012-01-01

An animal model with a cardiomyocyte-specific deletion of estrogen receptor alpha: functional, metabolic, and differential network analysis.

by Sriram Devanathan, Timothy Whitehead, George G Schweitzer, Nicole Fettig, Attila Kovacs, Kenneth S Korach, Brian N Finck, Kooresh I Shoghi
Published 2014-01-01

Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice[S]

by Angela M. Hall, Elizabeth M. Brunt, Zhouji Chen, Navin Viswakarma, Janardan K. Reddy, Nathan E. Wolins, Brian N. Finck
Published 2010-03-01

An ancestral role for the mitochondrial pyruvate carrier in glucose-stimulated insulin secretion

by Kyle S. McCommis, Wesley T. Hodges, Daniel K. Bricker, Dona R. Wisidagama, Vincent Compan, Maria S. Remedi, Carl S. Thummel, Brian N. Finck
Published 2016-08-01

A mutation in Site‐1 Protease is associated with a complex phenotype that includes episodic hyperCKemia and focal myoedema

by George G. Schweitzer, Connie Gan, Robert C. Bucelli, Daniel Wegner, Robert E. Schmidt, Marwan Shinawi, Brian N. Finck, Rita T. Brookheart
Published 2019-07-01

Multiple antisense oligonucleotides targeted against monoacylglycerol acyltransferase 1 (Mogat1) improve glucose metabolism independently of Mogat1

by Andrew J. Lutkewitte, Jason M. Singer, Trevor M. Shew, Michael R. Martino, Angela M. Hall, Mai He, Brian N. Finck
Published 2021-07-01

Lipin-1 Contributes to IL-4 Mediated Macrophage Polarization

by Sunitha Chandran, Robert M. Schilke, Cassidy M. R. Blackburn, Aila Yurochko, Rusella Mirza, Rona S. Scott, Brian N. Finck, Matthew D. Woolard
Published 2020-05-01

Metabolic importance of adipose tissue monoacylglycerol acyltransferase 1 in mice and humans

by Kim H.H. Liss, Andrew J. Lutkewitte, Terri Pietka, Brian N. Finck, Michael Franczyk, Jun Yoshino, Samuel Klein, Angela M. Hall
Published 2018-09-01

Liver-specific PGC-1beta deficiency leads to impaired mitochondrial function and lipogenic response to fasting-refeeding.

by Kari T Chambers, Zhouji Chen, Peter A Crawford, Xiaorong Fu, Shawn C Burgess, Ling Lai, Teresa C Leone, Daniel P Kelly, Brian N Finck
Published 2012-01-01

Fatty Acid Oxidation Promotes Cardiomyocyte Proliferation Rate but Does Not Change Cardiomyocyte Number in Infant Mice

by Tongtong Cao, Tongtong Cao, Daniela Liccardo, Ryan LaCanna, Xiaoying Zhang, Rong Lu, Brian N. Finck, Tani Leigh, Xiongwen Chen, Konstantinos Drosatos, Ying Tian
Published 2019-03-01

Liver-specific loss of lipin-1-mediated phosphatidic acid phosphatase activity does not mitigate intrahepatic TG accumulation in mice

by George G. Schweitzer, Zhouji Chen, Connie Gan, Kyle S. McCommis, Nisreen Soufi, Roman Chrast, Mayurranjan S. Mitra, Kui Yang, Richard W. Gross, Brian N. Finck
Published 2015-04-01

NADPH and Glutathione Redox Link TCA Cycle Activity to Endoplasmic Reticulum Homeostasis

by Erica R. Gansemer, Kyle S. McCommis, Michael Martino, Abdul Qaadir King-McAlpin, Matthew J. Potthoff, Brian N. Finck, Eric B. Taylor, D. Thomas Rutkowski
Published 2020-05-01

Hepatic monoacylglycerol acyltransferase 1 is induced by prolonged food deprivation to modulate the hepatic fasting response[S]

by Andrew J. Lutkewitte, Kyle S. McCommis, George G. Schweitzer, Kari T. Chambers, Mark J. Graham, Lingjue Wang, Gary J. Patti, Angela M. Hall, Brian N. Finck
Published 2019-03-01

Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver

by Angela M. Hall, Kou Kou, Zhouji Chen, Terri A. Pietka, Mrudula Kumar, Kevin M. Korenblat, Kyuha Lee, Kay Ahn, Elisa Fabbrini, Samuel Klein, Bryan Goodwin, Brian N. Finck
Published 2012-05-01

Myocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations

by Kari T. Chambers, Michael A. Cooper, Alison R. Swearingen, Rita T. Brookheart, George G. Schweitzer, Carla J. Weinheimer, Attila Kovacs, Timothy R. Koves, Deborah M. Muoio, Kyle S. McCommis, Brian N. Finck
Published 2021-05-01

Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH

by Sabine Daemen, Anastasiia Gainullina, Gowri Kalugotla, Li He, Mandy M. Chan, Joseph W. Beals, Kim H. Liss, Samuel Klein, Ariel E. Feldstein, Brian N. Finck, Maxim N. Artyomov, Joel D. Schilling
Published 2021-01-01