Outcome pre-specification requires sufficient detail to guard against outcome switching in clinical trials: a case study

by Brennan C. Kahan, Vipul Jairath
Published 2018-05-01

Blinded Outcome Assessment Was Infrequently Used and Poorly Reported in Open Trials.

by Brennan C Kahan, Sunita Rehal, Suzie Cro
Published 2015-01-01

How to design a pre-specified statistical analysis approach to limit p-hacking in clinical trials: the Pre-SPEC framework

by Brennan C. Kahan, Gordon Forbes, Suzie Cro
Published 2020-09-01

A comparison of approaches for adjudicating outcomes in clinical trials

by Brennan C. Kahan, Brian Feagan, Vipul Jairath
Published 2017-06-01

Evidence of unexplained discrepancies between planned and conducted statistical analyses: a review of randomised trials

by Suzie Cro, Gordon Forbes, Nicholas A. Johnson, Brennan C. Kahan
Published 2020-05-01

A comparison of methods to adjust for continuous covariates in the analysis of randomised trials

by Brennan C. Kahan, Helen Rushton, Tim P. Morris, Rhian M. Daniel
Published 2016-04-01

Estimands in published protocols of randomised trials: urgent improvement needed

by Brennan C. Kahan, Tim P. Morris, Ian R. White, James Carpenter, Suzie Cro
Published 2021-10-01

A four-step strategy for handling missing outcome data in randomised trials affected by a pandemic

by Suzie Cro, Tim P. Morris, Brennan C. Kahan, Victoria R. Cornelius, James R. Carpenter
Published 2020-08-01

Thoracoscopy and talc poudrage compared with intercostal drainage and talc slurry infusion to manage malignant pleural effusion: the TAPPS RCT

by Rahul Bhatnagar, Ramon Luengo-Fernandez, Brennan C Kahan, Najib M Rahman, Robert F Miller, Nick A Maskell
Published 2020-06-01

Analysis of multicenter clinical trials with very low event rates

by Jiyu Kim, Andrea B. Troxel, Scott D. Halpern, Kevin G. Volpp, Brennan C. Kahan, Tim P. Morris, Michael O. Harhay
Published 2020-11-01

MEMPHIS: a smartphone app using psychological approaches for women with chronic pelvic pain presenting to gynaecology clinics: a randomised feasibility trial

by Gordon Forbes, Brennan C Kahan, Liz Steed, Stephanie Taylor, Sian Newton, Clara Cantalapiedra Calvete, Judy Birch, Frank Röhricht, Elizabeth Ball
Published 2020-03-01

Novel Three-Day, Community-Based, Nonpharmacological Group Intervention for Chronic Musculoskeletal Pain (COPERS): A Randomised Clinical Trial.

by Stephanie J C Taylor, Dawn Carnes, Kate Homer, Brennan C Kahan, Natalia Hounsome, Sandra Eldridge, Anne Spencer, Tamar Pincus, Anisur Rahman, Martin Underwood
Published 2016-06-01

Randomised controlled trial and economic evaluation of a task-based weight management group programme

by Hayden McRobbie, Peter Hajek, Sarrah Peerbux, Brennan C. Kahan, Sandra Eldridge, Dominic Trépel, Steve Parrott, Chris Griffiths, Sarah Snuggs, Katie Myers Smith
Published 2019-04-01

Tackling obesity in areas of high social deprivation: clinical effectiveness and cost-effectiveness of a task-based weight management group programme – a randomised controlled tria...

by Hayden McRobbie, Peter Hajek, Sarrah Peerbux, Brennan C Kahan, Sandra Eldridge, Dominic Trépel, Steve Parrott, Chris Griffiths, Sarah Snuggs, Katie Myers Smith
Published 2016-10-01

Treatment estimands in clinical trials of patients hospitalised for COVID-19: ensuring trials ask the right questions

by Brennan C. Kahan, Tim P. Morris, Ian R. White, Conor D. Tweed, Suzie Cro, Darren Dahly, Tra My Pham, Hanif Esmail, Abdel Babiker, James R. Carpenter
Published 2020-09-01

Improving the self-management of chronic pain: COping with persistent Pain, Effectiveness Research in Self-management (COPERS)

by Stephanie JC Taylor, Dawn Carnes, Kate Homer, Tamar Pincus, Brennan C Kahan, Natalia Hounsome, Sandra Eldridge, Anne Spencer, Karla Diaz-Ordaz, Anisur Rahman, Tom S Mars, Jens Foell, Chris J Griffiths, Martin R Underwood
Published 2016-09-01

A randomised controlled trial of intravenous zoledronic acid in malignant pleural disease: a proof of principle pilot study.

by Amelia O Clive, Clare E Hooper, Anthony J Edey, Anna J Morley, Natalie Zahan-Evans, David Hall, Iain Lyburn, Paul White, Jeremy P Braybrooke, Iara Sequeiros, Stephen M Lyen, Tim Milton, Brennan C Kahan, Nick A Maskell
Published 2015-01-01

A national quality improvement programme to improve survival after emergency abdominal surgery: the EPOCH stepped-wedge cluster RCT

by Carol J Peden, Tim Stephens, Graham Martin, Brennan C Kahan, Ann Thomson, Kirsty Everingham, David Kocman, Jose Lourtie, Sharon Drake, Alan Girling, Richard Lilford, Kate Rivett, Duncan Wells, Ravi Mahajan, Peter Holt, Fan Yang, Simon Walker, Gerry Richardson, Sally Kerry, Iain Anderson, Dave Murray, David Cromwell, Mandeep Phull, Mike PW Grocott, Julian Bion, Rupert M Pearse
Published 2019-09-01