Interferon regulatory factor-8 is important for histone deacetylase inhibitor-mediated antitumor activity.

by Debarati Banik, A Nazmul H Khan, Even Walseng, Brahm H Segal, Scott I Abrams
Published 2012-01-01

NF-κB Inhibition after Cecal Ligation and Puncture Reduces Sepsis-Associated Lung Injury without Altering Bacterial Host Defense

by Hui Li, Wei Han, Vasilly Polosukhin, Fiona E. Yull, Brahm H. Segal, Can-Mao Xie, Timothy S. Blackwell
Published 2013-01-01

Mitochondrial hypoxic stress induces widespread RNA editing by APOBEC3G in natural killer cells

by Shraddha Sharma, Jianmin Wang, Emad Alqassim, Scott Portwood, Eduardo Cortes Gomez, Orla Maguire, Per H. Basse, Eunice S. Wang, Brahm H. Segal, Bora E. Baysal
Published 2019-02-01

Mitochondrial DNA released by trauma induces neutrophil extracellular traps.

by Kiyoshi Itagaki, Elzbieta Kaczmarek, Yen Ting Lee, I Tien Tang, Burak Isal, Yashar Adibnia, Nicola Sandler, Melissa J Grimm, Brahm H Segal, Leo E Otterbein, Carl J Hauser
Published 2015-01-01

Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense.

by R Robert Vethanayagam, Nikolaos G Almyroudis, Melissa J Grimm, David C Lewandowski, Christine T N Pham, Timothy S Blackwell, Ruta Petraitiene, Vidmantas Petraitis, Thomas J Walsh, Constantin F Urban, Brahm H Segal
Published 2011-01-01

Tracing Conidial Fate and Measuring Host Cell Antifungal Activity Using a Reporter of Microbial Viability in the Lung

by Anupam Jhingran, Katrina B. Mar, Debra K. Kumasaka, Sue E. Knoblaugh, Lisa Y. Ngo, Brahm H. Segal, Yoichiro Iwakura, Clifford A. Lowell, Jessica A. Hamerman, Xin Lin, Tobias M. Hohl
Published 2012-12-01

Myeloid-derived suppressor cells modulate immune responses independently of NADPH oxidase in the ovarian tumor microenvironment in mice.

by Heidi E Godoy, A Nazmul H Khan, R Robert Vethanayagam, Melissa J Grimm, Kelly L Singel, Nonna Kolomeyevskaya, Kevin J Sexton, Anupama Parameswaran, Scott I Abrams, Kunle Odunsi, Brahm H Segal
Published 2013-01-01

T-cell CX3CR1 expression as a dynamic blood-based biomarker of response to immune checkpoint inhibitors

by Takayoshi Yamauchi, Toshifumi Hoki, Takaaki Oba, Vaibhav Jain, Hongbin Chen, Kristopher Attwood, Sebastiano Battaglia, Saby George, Gurkamal Chatta, Igor Puzanov, Carl Morrison, Kunle Odunsi, Brahm H. Segal, Grace K. Dy, Marc S. Ernstoff, Fumito Ito
Published 2021-03-01

RNA editing enzyme APOBEC3A promotes pro-inflammatory M1 macrophage polarization

by Emad Y. Alqassim, Shraddha Sharma, A. N. M. Nazmul H. Khan, Tiffany R. Emmons, Eduardo Cortes Gomez, Abdulrahman Alahmari, Kelly L. Singel, Jaron Mark, Bruce A. Davidson, A. J. Robert McGray, Qian Liu, Brian D. Lichty, Kirsten B. Moysich, Jianmin Wang, Kunle Odunsi, Brahm H. Segal, Bora E. Baysal
Published 2021-01-01

NADPH oxidase limits innate immune responses in the lungs in mice.

by Brahm H Segal, Wei Han, Jennifer J Bushey, Myungsoo Joo, Zahida Bhatti, Joy Feminella, Carly G Dennis, R Robert Vethanayagam, Fiona E Yull, Maegan Capitano, Paul K Wallace, Hans Minderman, John W Christman, Michael B Sporn, Jefferson Chan, Donald C Vinh, Steven M Holland, Luigina R Romani, Sarah L Gaffen, Michael L Freeman, Timothy S Blackwell
Published 2010-03-01