Antiviral Agents Article Brazil Brazilian Cost-Benefit Analysis Drug Costs Drug Therapy, Combination Female Health Care Costs Hepatitis C, Chronic Humans Interferon-alpha Male Markov Chains Markov chain Middle Aged N-(3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl)-3-(2-((((1,1-dimethylethyl)amino)carbonyl)amino)-3,3-dimethyl-1-oxobutyl)-6,6-dimethyl-3-azabicyclo(3.1.0)hexan-2-carboxamide Oligopeptides Proline Public Health Practice Quality-Adjusted Life Years Ribavirin Treatment Outcome alpha interferon antivirus agent boceprevir chronic hepatitis C clinical effectiveness clinical outcome combination drug therapy