Temporal Detection and Phylogenetic Assessment of SARS-CoV-2 in Municipal Wastewater

by Artem Nemudryi, Anna Nemudraia, Tanner Wiegand, Kevin Surya, Murat Buyukyoruk, Calvin Cicha, Karl K. Vanderwood, Royce Wilkinson, Blake Wiedenheft
Published 2020-09-01

Type I-E CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition.

by Edze R Westra, Ekaterina Semenova, Kirill A Datsenko, Ryan N Jackson, Blake Wiedenheft, Konstantin Severinov, Stan J J Brouns
Published 2013-01-01

AcrIF9 tethers non-sequence specific dsDNA to the CRISPR RNA-guided surveillance complex

by Marscha Hirschi, Wang-Ting Lu, Andrew Santiago-Frangos, Royce Wilkinson, Sarah M. Golden, Alan R. Davidson, Gabriel C. Lander, Blake Wiedenheft
Published 2020-06-01

Something old, something new, something borrowed; how the thermoacidophilic archaeon Sulfolobus solfataricus responds to oxidative stress.

by Walid S Maaty, Blake Wiedenheft, Pavel Tarlykov, Nathan Schaff, Joshua Heinemann, Jim Robison-Cox, Jacob Valenzuela, Amanda Dougherty, Paul Blum, C Martin Lawrence, Trevor Douglas, Mark J Young, Brian Bothner
Published 2009-09-01

Metatranscriptome Analysis of Sympatric Bee Species Identifies Bee Virus Variants and a New Virus, Andrena-Associated Bee Virus-1

by Katie F. Daughenbaugh, Idan Kahnonitch, Charles C. Carey, Alexander J. McMenamin, Tanner Wiegand, Tal Erez, Naama Arkin, Brian Ross, Blake Wiedenheft, Asaf Sadeh, Nor Chejanovsky, Yael Mandelik, Michelle L. Flenniken
Published 2021-02-01

Intrinsic signal amplification by type III CRISPR-Cas systems provides a sequence-specific SARS-CoV-2 diagnostic

by Andrew Santiago-Frangos, Laina N. Hall, Anna Nemudraia, Artem Nemudryi, Pushya Krishna, Tanner Wiegand, Royce A. Wilkinson, Deann T. Snyder, Jodi F. Hedges, Calvin Cicha, Helen H. Lee, Ava Graham, Mark A. Jutila, Matthew P. Taylor, Blake Wiedenheft
Published 2021-06-01