Development of novel (1-H) benzimidazole bearing pyrimidine-trione based MAO-A inhibitors: Synthesis, docking studies and antidepressant activity

by Bijo Mathew, Jerad Suresh, S. Anbazhagan
Published 2016-09-01

Synthesis and PASS-assisted in silico approach of some novel 2-substituted benzimidazole bearing a pyrimidine-2, 4, 6(trione) system as mucomembranous protector

by Bijo Mathew, Jerad Suresh, Socklingam Anbazhagan
Published 2013-01-01

Discovery of some novel imines of 2-amino, 5-thio, 1,3,4-thiadiazole as mucomembranous protector. Synthesis, anti-oxidant activity and in silico PASS approach

by Bijo Mathew, Jerad Suresh, S. Anbazhagan, N. Chidambaranathan
Published 2016-09-01

Toxic tau: structural origins of tau aggregation in Alzheimer's disease

by Abdullah Al Mamun, Md Sahab Uddin, Bijo Mathew, Ghulam Md Ashraf
Published 2020-01-01

Determination of in vitro free radical scavenging and antiproliferative effect of Pennisetum alopecuroides on cultured A549 human lung cancer cells

by Githa Elizabeth Mathew, Bijo Mathew, S Gokul, Rahul Krishna, M P Farisa
Published 2015-01-01

Design of 1-(furan-2-yl)-N-(5-substituted phenyl-1, 3, 4-thiadiazol-2-yl) methanimine derivatives as Enoyl-ACP reductase inhibitors: Synthesis, molecular docking studies and antitu...

by Bijo Mathew, Githa Elizabeth Mathew, George Sonia, Anila Kumar, Neethu P Charles, Palanisamy Kumar
Published 2013-05-01

Design of 1-(furan-2-yl)-N-(5-substituted phenyl-1, 3, 4-thiadiazol-2-yl) methanimine derivatives as Enoyl-ACP reductase inhibitors: Synthesis, molecular docking studies and anti-t...

by Bijo Mathew, Githa Elizabeth Mathew, George Sonia, Anila Kumar, Neethu P Charles, Palanisamy Kumar
Published 2013-08-01

Synthesis, Cytotoxicity and Anti−Proliferative Activity Against AGS Cells of New 3(2<i>H</i>)−Pyridazinone Derivatives Endowed with a Piperazinyl Linker

by Mehmet Abdullah Alagöz, Zeynep Özdemir, Mehtap Uysal, Simone Carradori, Marialucia Gallorini, Alessia Ricci, Susi Zara, Bijo Mathew
Published 2021-02-01

Insights into an Immunotherapeutic Approach to Combat Multidrug Resistance in Hepatocellular Carcinoma

by Aswathy R. Devan, Ayana R. Kumar, Bhagyalakshmi Nair, Nikhil Ponnoor Anto, Amitha Muraleedharan, Bijo Mathew, Hoon Kim, Lekshmi R. Nath
Published 2021-07-01

Synthesis and biological evaluation of new 3(2H)-pyridazinone derivatives as non-toxic anti-proliferative compounds against human colon carcinoma HCT116 cells

by Zeynep Özdemir, Semra Utku, Bijo Mathew, Simone Carradori, Giustino Orlando, Simonetta Di Simone, Mehmet Abdullah Alagöz, Azime Berna Özçelik, Mehtap Uysal, Claudio Ferrante
Published 2020-01-01

Therapeutic Potential of Polyphenols in the Management of Diabetic Neuropathy

by Md. Tanvir Kabir, Nuzhat Tabassum, Md. Sahab Uddin, Faissal Aziz, Tapan Behl, Bijo Mathew, Md. Habibur Rahman, Raushanara Akter, Abdur Rauf, Lotfi Aleya
Published 2021-01-01

Design, Synthesis, and Biological Evaluation of Pyridazinones Containing the (2-Fluorophenyl) Piperazine Moiety as Selective MAO-B Inhibitors

by Muhammed Çeçen, Jong Min Oh, Zeynep Özdemir, Saliha Ebru Büyüktuncel, Mehtap Uysal, Mohamed A. Abdelgawad, Arafa Musa, Nicola Gambacorta, Orazio Nicolotti, Bijo Mathew, Hoon Kim
Published 2020-11-01

Novel Class of Chalcone Oxime Ethers as Potent Monoamine Oxidase-B and Acetylcholinesterase Inhibitors

by Jong Min Oh, T. M. Rangarajan, Reeta Chaudhary, Rishi Pal Singh, Manjula Singh, Raj Pal Singh, Anna Rita Tondo, Nicola Gambacorta, Orazio Nicolotti, Bijo Mathew, Hoon Kim
Published 2020-05-01

Novel Anti-Alzheimer’s Therapeutic Molecules Targeting Amyloid Precursor Protein Processing

by Md. Sahab Uddin, Md. Tanvir Kabir, Philippe Jeandet, Bijo Mathew, Ghulam Md Ashraf, Asma Perveen, May N. Bin-Jumah, Shaker A. Mousa, Mohamed M. Abdel-Daim
Published 2020-01-01

Morpholine-based chalcones as dual-acting monoamine oxidase-B and acetylcholinesterase inhibitors: synthesis and biochemical investigations

by Rani Sasidharan, Bo Hyun Eom, Jeong Hyun Heo, Jong Eun Park, Mohamed A. Abdelgawad, Arafa Musa, Nicola Gambacorta, Orazio Nicolotti, Sreedharannair Leelabaiamma Manju, Bijo Mathew, Hoon Kim
Published 2021-01-01

Trimethoxylated Halogenated Chalcones as Dual Inhibitors of MAO-B and BACE-1 for the Treatment of Neurodegenerative Disorders

by Payyalot Koyiparambath Vishal, Jong Min Oh, Ahmed Khames, Mohamed A. Abdelgawad, Aathira Sujathan Nair, Lekshmi R. Nath, Nicola Gambacorta, Fulvio Ciriaco, Orazio Nicolotti, Hoon Kim, Bijo Mathew
Published 2021-06-01

Molecular Insight into the Therapeutic Promise of Flavonoids against Alzheimer’s Disease

by Md. Sahab Uddin, Md. Tanvir Kabir, Kamal Niaz, Philippe Jeandet, Christophe Clément, Bijo Mathew, Abdur Rauf, Kannan R.R. Rengasamy, Eduardo Sobarzo-Sánchez, Ghulam Md Ashraf, Lotfi Aleya
Published 2020-03-01

Combination Drug Therapy for the Management of Alzheimer’s Disease

by Md. Tanvir Kabir, Md. Sahab Uddin, Abdullah Al Mamun, Philippe Jeandet, Lotfi Aleya, Rasha A. Mansouri, Ghulam Md Ashraf, Bijo Mathew, May N. Bin-Jumah, Mohamed M. Abdel-Daim
Published 2020-05-01

Synthesis of <i>N</i>′-(4-/3-/2-/Non-substituted benzylidene)-4-[(4-methylphenyl)sulfonyloxy] Benzohydrazides and Evaluation of Their Inhibitory Activities against Monoamine Oxidas...

by Hasan Erdinç Sellitepe, Jong Min Oh, İnci Selin Doğan, Sercan Yildirim, Ahmet Buğra Aksel, Geum Seok Jeong, Ahmed Khames, Mohamed A. Abdelgawad, Nicola Gambacorta, Orazio Nicolotti, Bijo Mathew, Hoon Kim
Published 2021-06-01

Development of Halogenated Pyrazolines as Selective Monoamine Oxidase-B Inhibitors: Deciphering via Molecular Dynamics Approach

by Aathira Sujathan Nair, Jong-Min Oh, Vishal Payyalot Koyiparambath, Sunil Kumar, Sachithra Thazhathuveedu Sudevan, Opeyemi Soremekun, Mahmoud E. Soliman, Ahmed Khames, Mohamed A. Abdelgawad, Leena K. Pappachen, Bijo Mathew, Hoon Kim
Published 2021-05-01