11-Keto-α-Boswellic Acid, a Novel Triterpenoid from <i>Boswellia</i> spp. with Chemotaxonomic Potential and Antitumor Activity against Triple-Negative Breast Cancer Cells

by Michael Schmiech, Judith Ulrich, Sophia Johanna Lang, Berthold Büchele, Christian Paetz, Alexis St‑Gelais, Tatiana Syrovets, Thomas Simmet
Published 2021-01-01

A boswellic acid-containing extract ameliorates schistosomiasis liver granuloma and fibrosis through regulating NF-κB signaling in mice.

by Miao Liu, Qingsi Wu, Peng Chen, Berthold Büchele, Maohong Bian, Shengjian Dong, Dake Huang, Cuiping Ren, Yuxia Zhang, Xin Hou, Thomas Simmet, Jijia Shen
Published 2014-01-01

Drug targeting CYP2E1 for the treatment of early-stage alcoholic steatohepatitis.

by Torsten Diesinger, Vyacheslav Buko, Alfred Lautwein, Radovan Dvorsky, Elena Belonovskaya, Oksana Lukivskaya, Elena Naruta, Siarhei Kirko, Viktor Andreev, Dominik Buckert, Sebastian Bergler, Christian Renz, Edith Schneider, Florian Kuchenbauer, Mukesh Kumar, Cagatay Günes, Berthold Büchele, Thomas Simmet, Dieter Müller-Enoch, Thomas Wirth, Thomas Haehner
Published 2020-01-01

A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma

by Torsten Diesinger, Alfred Lautwein, Sebastian Bergler, Dominik Buckert, Christian Renz, Radovan Dvorsky, Vyacheslav Buko, Siarhei Kirko, Edith Schneider, Florian Kuchenbauer, Mukesh Kumar, Cagatay Günes, Felicitas Genze, Berthold Büchele, Thomas Simmet, Martin Haslbeck, Kai Masur, Thomas Barth, Dieter Müller-Enoch, Thomas Wirth, Thomas Haehner
Published 2021-01-01