A protective and safe intranasal RSV vaccine based on a recombinant prefusion-like form of the F protein bound to bacterium-like particles.

by Alan Rigter, Ivy Widjaja, Hanneke Versantvoort, Frank E J Coenjaerts, Maarten van Roosmalen, Kees Leenhouts, Peter J M Rottier, Bert Jan Haijema, Cornelis A M de Haan
Published 2013-01-01

Recombinant Soluble Respiratory Syncytial Virus F Protein That Lacks Heptad Repeat B, Contains a GCN4 Trimerization Motif and Is Not Cleaved Displays Prefusion-Like Characteristics...

by Ivy Widjaja, Alan Rigter, Shamir Jacobino, Frank J M van Kuppeveld, Kees Leenhouts, Concepción Palomo, Jose A Melero, Jeanette H W Leusen, Bert Jan Haijema, Peter J M Rottier, Cornelis A M de Haan
Published 2015-01-01