Repurposing drugs for the treatment and control of helminth infections

by Gordana Panic, Urs Duthaler, Benjamin Speich, Jennifer Keiser
Published 2014-12-01

Comparison of randomized controlled trials discontinued or revised for poor recruitment and completed trials with the same research question: a matched qualitative study

by Matthias Briel, Benjamin Speich, Erik von Elm, Viktoria Gloy
Published 2019-12-01

One mean to rule them all? The arithmetic mean based egg reduction rate can be misleading when estimating anthelminthic drug efficacy in clinical trials.

by Wendelin Moser, Jennifer Keiser, Benjamin Speich, Somphou Sayasone, Stefanie Knopp, Jan Hattendorf
Published 2020-04-01

Effect of sanitation on soil-transmitted helminth infection: systematic review and meta-analysis.

by Kathrin Ziegelbauer, Benjamin Speich, Daniel Mäusezahl, Robert Bos, Jennifer Keiser, Jürg Utzinger
Published 2012-01-01

Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms: revival of an old drug.

by Jennifer Keiser, Lucienne Tritten, Angelika Silbereisen, Benjamin Speich, Roberto Adelfio, Mireille Vargas
Published 2013-01-01

Dexmedetomidine in prevention and treatment of postoperative and intensive care unit delirium: a systematic review and meta-analysis

by Julian Flükiger, Alexa Hollinger, Benjamin Speich, Vera Meier, Janna Tontsch, Tatjana Zehnder, Martin Siegemund
Published 2018-09-01

Efficacy and safety of nitazoxanide, albendazole, and nitazoxanide-albendazole against Trichuris trichiura infection: a randomized controlled trial.

by Benjamin Speich, Shaali M Ame, Said M Ali, Rainer Alles, Jan Hattendorf, Jürg Utzinger, Marco Albonico, Jennifer Keiser
Published 2012-01-01

Efficacy and safety of co-administered ivermectin plus albendazole for treating soil-transmitted helminths: A systematic review, meta-analysis and individual patient data analysis.

by Marta S Palmeirim, Eveline Hürlimann, Stefanie Knopp, Benjamin Speich, Vicente Belizario, Serene A Joseph, Michel Vaillant, Piero Olliaro, Jennifer Keiser
Published 2018-04-01

How long can stool samples be fixed for an accurate diagnosis of soil-transmitted helminth infection using Mini-FLOTAC?

by Beatrice Barda, Marco Albonico, Davide Ianniello, Shaali M Ame, Jennifer Keiser, Benjamin Speich, Laura Rinaldi, Giuseppe Cringoli, Roberto Burioni, Antonio Montresor, Jürg Utzinger
Published 2015-04-01

Clinical evaluation for morbidity associated with soil-transmitted helminth infection in school-age children on Pemba Island, Tanzania.

by Isaac I Bogoch, Benjamin Speich, Nathan C Lo, Wendelin Moser, David Croll, Said M Ali, Shaali M Ame, Jürg Utzinger, Jason R Andrews, Jennifer Keiser
Published 2019-07-01

Single-dose versus 3-day cotrimoxazole prophylaxis in transurethral resection or greenlight laser vaporisation of the prostate: study protocol for a multicentre randomised placebo...

by Benjamin Speich, Kathrin Bausch, Jan A. Roth, Lars G. Hemkens, Hannah Ewald, Deborah R. Vogt, Nicole Bruni, Stefanie Deuster, Hans-H. Seifert, Andreas F. Widmer
Published 2019-02-01

Diagnostic accuracy of Kato-Katz and FLOTAC for assessing anthelmintic drug efficacy.

by Stefanie Knopp, Benjamin Speich, Jan Hattendorf, Laura Rinaldi, Khalfan A Mohammed, I Simba Khamis, Alisa S Mohammed, Marco Albonico, David Rollinson, Hanspeter Marti, Giuseppe Cringoli, Jürg Utzinger
Published 2011-01-01

The Comparative Effectiveness of Innovative Treatments for Cancer (CEIT-Cancer) project: Rationale and design of the database and the collection of evidence available at approval o...

by Aviv Ladanie, Benjamin Speich, Florian Naudet, Arnav Agarwal, Tiago V. Pereira, Francesco Sclafani, Juan Martin-Liberal, Thomas Schmid, Hannah Ewald, John P. A. Ioannidis, Heiner C. Bucher, Benjamin Kasenda, Lars G. Hemkens
Published 2018-09-01

UMBRELLA protocol: systematic reviews of multivariable biomarker prognostic models developed to predict clinical outcomes in patients with heart failure

by Maria D. L. A. Vazquez-Montes, Thomas P. A. Debray, Kathryn S. Taylor, Benjamin Speich, Nicholas Jones, Gary S. Collins, F. D. R. Richard Hobbs, Emmanuella Magriplis, Hugo Maruri-Aguilar, Karel G. M. Moons, John Parissis, Rafael Perera, Nia Roberts, Clare J. Taylor, Nikolaos P. E. Kadoglou, Marialena Trivella, on behalf of the proBHF group
Published 2020-08-01

Resource use, costs, and approval times for planning and preparing a randomized clinical trial before and after the implementation of the new Swiss human research legislation.

by Benjamin Speich, Nadine Schur, Dmitry Gryaznov, Belinda von Niederhäusern, Lars G Hemkens, Stefan Schandelmaier, Alain Amstutz, Benjamin Kasenda, Christiane Pauli-Magnus, Elena Ojeda-Ruiz, Yuki Tomonaga, Kimberly McCord, Alain Nordmann, Erik von Elm, Matthias Briel, Matthias Schwenkglenks, a collaboration of the MARTA (MAking Randomized Trials Affordable) and ASPIRE (Adherence to Standard Protocol Items: REcommendations for interventional trials) Study Groups
Published 2019-01-01

Prediction of RECRUITment In randomized clinical Trials (RECRUIT-IT)—rationale and design for an international collaborative study

by Benjamin Kasenda, Junhao Liu, Yu Jiang, Byron Gajewski, Cen Wu, Erik von Elm, Stefan Schandelmaier, Giusi Moffa, Sven Trelle, Andreas Michael Schmitt, Amanda K. Herbrand, Viktoria Gloy, Benjamin Speich, Sally Hopewell, Lars G. Hemkens, Constantin Sluka, Kris McGill, Maureen Meade, Deborah Cook, Francois Lamontagne, Jean-Marc Tréluyer, Anna-Bettina Haidich, John P. A. Ioannidis, Shaun Treweek, Matthias Briel
Published 2020-08-01

Rationale and design of repeated cross-sectional studies to evaluate the reporting quality of trial protocols: the Adherence to SPIrit REcommendations (ASPIRE) study and associated...

by Dmitry Gryaznov, Ayodele Odutayo, Belinda von Niederhäusern, Benjamin Speich, Benjamin Kasenda, Elena Ojeda-Ruiz, Anette Blümle, Stefan Schandelmaier, Dominik Mertz, Yuki Tomonaga, Alain Amstutz, Christiane Pauli-Magnus, Viktoria Gloy, Karin Bischoff, Katharina Wollmann, Laura Rehner, Szimonetta Lohner, Joerg J. Meerpohl, Alain Nordmann, Katharina Klatte, Nilabh Ghosh, Ala Taji Heravi, Jacqueline Wong, Ngai Chow, Patrick Jiho Hong, Kimberly Mc Cord, Sirintip Sricharoenchai, Jason W. Busse, Arnav Agarwal, Ramon Saccilotto, Matthias Schwenkglenks, Giusi Moffa, Lars G. Hemkens, Sally Hopewell, Erik von Elm, Matthias Briel
Published 2020-10-01

The worldwide clinical trial research response to the COVID-19 pandemic - the first 100 days [version 1; peer review: 2 approved]

by Perrine Janiaud, Cathrine Axfors, Janneke van't Hooft, Ramon Saccilotto, Arnav Agarwal, Christian Appenzeller-Herzog, Despina G. Contopoulos-Ioannidis, Valentin Danchev, Ulrich Dirnagl, Hannah Ewald, Gerald Gartlehner, Steven N. Goodman, Noah A. Haber, Angeliki Diotima Ioannidis, John P. A. Ioannidis, Mark P. Lythgoe, Wenyan Ma, Malcolm Macleod, Mario Malički, Joerg J. Meerpohl, Yan Min, David Moher, Blin Nagavci, Florian Naudet, Christiane Pauli-Magnus, Jack W. O'Sullivan, Nico Riedel, Jan A. Roth, Mandy Sauermann, Stefan Schandelmaier, Andreas M. Schmitt, Benjamin Speich, Paula R. Williamson, Lars G. Hemkens
Published 2020-10-01

The worldwide clinical trial research response to the COVID-19 pandemic - the first 100 days [version 2; peer review: 2 approved]

by Perrine Janiaud, Cathrine Axfors, Janneke van't Hooft, Ramon Saccilotto, Arnav Agarwal, Christian Appenzeller-Herzog, Despina G. Contopoulos-Ioannidis, Valentin Danchev, Ulrich Dirnagl, Hannah Ewald, Gerald Gartlehner, Steven N. Goodman, Noah A. Haber, Angeliki Diotima Ioannidis, John P. A. Ioannidis, Mark P. Lythgoe, Wenyan Ma, Malcolm Macleod, Mario Malički, Joerg J. Meerpohl, Yan Min, David Moher, Blin Nagavci, Florian Naudet, Christiane Pauli-Magnus, Jack W. O'Sullivan, Nico Riedel, Jan A. Roth, Mandy Sauermann, Stefan Schandelmaier, Andreas M. Schmitt, Benjamin Speich, Paula R. Williamson, Lars G. Hemkens
Published 2020-10-01