RNA Is a Double-Edged Sword in ALS Pathogenesis

by Benjamin L. Zaepfel, Benjamin L. Zaepfel, Jeffrey D. Rothstein, Jeffrey D. Rothstein
Published 2021-07-01

Failure to Deliver and Translate—New Insights into RNA Dysregulation in ALS

by Alyssa N. Coyne, Alyssa N. Coyne, Benjamin L. Zaepfel, Daniela C. Zarnescu, Daniela C. Zarnescu, Daniela C. Zarnescu
Published 2017-08-01

UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction

by Benjamin L. Zaepfel, Zhe Zhang, Kirstin Maulding, Alyssa N. Coyne, Weiwei Cheng, Lindsey R. Hayes, Thomas E. Lloyd, Shuying Sun, Jeffrey D. Rothstein
Published 2021-03-01

Post-transcriptional Inhibition of Hsc70-4/HSPA8 Expression Leads to Synaptic Vesicle Cycling Defects in Multiple Models of ALS

by Alyssa N. Coyne, Ileana Lorenzini, Ching-Chieh Chou, Meaghan Torvund, Robert S. Rogers, Alexander Starr, Benjamin L. Zaepfel, Jennifer Levy, Jeffrey Johannesmeyer, Jacob C. Schwartz, Hiroshi Nishimune, Konrad Zinsmaier, Wilfried Rossoll, Rita Sattler, Daniela C. Zarnescu
Published 2017-10-01