A System of RNA Modifications and Biased Codon Use Controls Cellular Stress Response at the Level of Translation

by Begley, Thomas J., Dedon, Peter C
Published 2015

tRNA modifications regulate translation during cellular stress

by Gu, Chen, Begley, Thomas J., Dedon, Peter C.
Published 2015

Codon-biased translation can be regulated by wobble-base tRNA modification systems during cellular stress responses

by Endres, Lauren, Dedon, Peter C., Begley, Thomas J.
Published 2015

The Versatile Roles of the tRNA Epitranscriptome during Cellular Responses to Toxic Exposures and Environmental Stress

by Huber, Sabrina M, Leonardi, Andrea, Dedon, Peter C, Begley, Thomas J.
Published 2019

Lifestyle modifications: coordinating the tRNA epitranscriptome with codon bias to adapt translation during stress responses

by Chan, Cheryl, Begley, Thomas J., Pham, Phuong M., Dedon, Peter C
Published 2019

Phosphorylation of human TRM9L integrates multiple stress-signaling pathways for tumor growth suppression

by Ramos, Jillian, Begley, Ulrike, Fu, Dragony, Begley, Thomas J., Gu, Chen, Dedon, Peter C
Published 2018

Gene- and genome-based analysis of significant codon patterns in yeast, rat and mice genomes with the CUT Codon UTilization tool

by Doyle, Francis, Leonardi, Andrea, Endres, Lauren, Tenenbaum, Scott A., Begley, Thomas J., Dedon, Peter C
Published 2018

Trm9-Catalyzed tRNA Modifications Regulate Global Protein Expression by Codon-Biased Translation

by Deng, Wenjun, Babu, I. Ramesh, Su, Dan, Yin, Shanye, Begley, Thomas J., Dedon, Peter C.
Published 2016

Anc1, a Protein Associated with Multiple Transcription Complexes, Is Involved in Postreplication Repair Pathway in S-cerevisiae

by Erlich, Rachel L., Fry, Rebecca C., Begley, Thomas J., Daee, Danielle L., Lahue, Robert S., Samson, Leona D.
Published 2010

A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress

by Chan, Tsz Yan Clement, Dyavaiah, Madhu, DeMott, Michael S., Taghizadeh, Koli, Dedon, Peter C., Begley, Thomas J.
Published 2011

Highly Predictive Reprogramming of tRNA Modifications Is Linked to Selective Expression of Codon-Biased Genes

by Begley, Thomas J., Li, Fugen, Chan, Clement T. Y., Deng, Wenjun, DeMott, Michael S, Babu, I. Ramesh, Dedon, Peter C
Published 2017

Increased tRNA modification and gene-specific codon usage regulate cell cycle progression during the DNA damage response

by Patil, Ashish, Dyavaiah, Madhu, Joseph, Fraulin, Rooney, John P., Chan, Tsz Yan Clement, Dedon, Peter C., Begley, Thomas J.
Published 2014

Alkbh8 Regulates Selenocysteine-Protein Expression to Protect against Reactive Oxygen Species Damage

by Endres, Lauren, Begley, Ulrike, Clark, Ryan, Gu, Chen, Dziergowska, Agnieszka, Małkiewicz, Andrzej, Melendez, J. Andres, Dedon, Peter C., Begley, Thomas J.
Published 2015

Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins

by Chan, Tsz Yan Clement, Pang, Yan Ling Joy, Deng, Wenjun, Indrakanti, Ramesh Babu, Dyavaiah, Madhu, Begley, Thomas J., Dedon, Peter C.
Published 2013

Human AlkB Homolog ABH8 Is a tRNA Methyltransferase Required for Wobble Uridine Modification and DNA Damage Survival

by Fu, Dragony, Brophy, Jennifer Ann, Atmore, Kyle Aaquil, Begley, Ulrike, Begley, Thomas J., Paules, Richard S., Chan, Clement T. Y., Dedon, Peter C, Samson, Leona D
Published 2011

Quantitative analysis of tRNA modifications by HPLC-coupled mass spectrometry

by Su, Dan, Gu, Chen, Lim, Kok Seong, Chionh, Yok Hian, Chan, Clement T. Y., McBee, Megan E., Russell, Brandon S., Ramesh Babu, I., Begley, Thomas J., Dedon, Peter C.
Published 2015

Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast

by Pollo-Oliveira, Leticia, Klassen, Roland, Davis, Nick, Ciftci, Akif, Bacusmo, Jo Marie, Martinelli, Maria, DeMott, Michael S., Begley, Thomas J., Dedon, Peter C, Schaffrath, Raffael, de Crécy-Lagard, Valérie
Published 2020

tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence

by Chionh, Yok Hian, McBee, Megan, Babu, I. Ramesh, Hia, Fabian, Lin, Wenwei, Zhao, Wei, Cao, Jianshu, Dziergowska, Agnieszka, Malkiewicz, Andrzej, Begley, Thomas J., Alonso, Sylvie, Dedon, Peter C.
Published 2016