Translating Mechanism of Regulatory Action of Tolerogenic Dendritic Cells to Monitoring Endpoints in Clinical Trials

by Jessica S. Suwandi, Tatjana Nikolic, Bart O. Roep, Bart O. Roep
Published 2017-11-01

Islet-Resident Dendritic Cells and Macrophages in Type 1 Diabetes: In Search of Bigfoot’s Print

by Henner Zirpel, Bart O. Roep
Published 2021-04-01

A Future for Autologous Hematopoietic Stem Cell Transplantation in Type 1 Diabetes

by Kayleigh M. van Megen, Ernst-Jan T. van ’t Wout, Stephen J. Forman, Bart O. Roep, Bart O. Roep
Published 2018-04-01

Self-glycolipids modulate dendritic cells changing the cytokine profiles of committed autoreactive T cells.

by Karsten Buschard, Jan-Eric Månsson, Bart O Roep, Tatjana Nikolic
Published 2012-01-01

Activated Mesenchymal Stromal Cells Process and Present Antigens Regulating Adaptive Immunity

by Kayleigh M. van Megen, Ernst-Jan T. van 't Wout, Julia Lages Motta, Julia Lages Motta, Bernice Dekker, Tatjana Nikolic, Bart O. Roep, Bart O. Roep
Published 2019-04-01

Adenoviral vectors stimulate glucagon transcription in human mesenchymal stem cells expressing pancreatic transcription factors.

by Arnaud Zaldumbide, Françoise Carlotti, Manuel A Gonçalves, Shoshan Knaän-Shanzer, Steve J Cramer, Bart O Roep, Emmanuel J H J Wiertz, Rob C Hoeben
Published 2012-01-01

Heterogeneity of circulating CD8 T-cells specific to islet, neo-antigen and virus in patients with type 1 diabetes mellitus.

by Sandra Laban, Jessica S Suwandi, Vincent van Unen, Jos Pool, Joris Wesselius, Thomas Höllt, Nicola Pezzotti, Anna Vilanova, Boudewijn P F Lelieveldt, Bart O Roep
Published 2018-01-01

Intra-pancreatic tissue-derived mesenchymal stromal cells: a promising therapeutic potential with anti-inflammatory and pro-angiogenic profiles

by Bashar Khiatah, Meirigeng Qi, Weiting Du, Kuan T-Chen, Kayleigh M. van Megen, Rachel G. Perez, Jeffrey S. Isenberg, Fouad Kandeel, Bart O. Roep, Hsun Teresa Ku, Ismail H. Al-Abdullah
Published 2019-11-01

Serum Cytokines as Biomarkers in Islet Cell Transplantation for Type 1 Diabetes.

by Cornelis R van der Torren, Annemarie A Verrijn Stuart, DaHae Lee, Jenny Meerding, Ursule van de Velde, Daniel Pipeleers, Pieter Gillard, Bart Keymeulen, Wilco de Jager, Bart O Roep
Published 2016-01-01

Identification of Donor Origin and Condition of Transplanted Islets in Situ in the Liver of a Type 1 Diabetic Recipient

by Cornelis R. Van Der Torren, Jessica S. Suwandi, Dahae Lee, Ernst-Jan T. Van't Wout, Gaby Duinkerken, Godelieve Swings, Arend Mulder, Frans H. J. Claas, Zhidong Ling, Pieter Gillard, Bart Keymeulen, Peter In't Veld, Bart O. Roep
Published 2017-01-01

Alcohol facilitates CD1d loading, subsequent activation of NKT cells, and reduces the incidence of diabetes in NOD mice.

by Karsten Buschard, Axel Kornerup Hansen, Karen Jensen, Dicky J Lindenbergh-Kortleve, Lilian F de Ruiter, Thomas C Krohn, Majbritt R Hufeldt, Finn K Vogensen, Bent Aasted, Thomas Osterbye, Bart O Roep, Colin de Haar, Edward E Nieuwenhuis
Published 2011-01-01

Islet-specific CTL cloned from a type 1 diabetes patient cause beta-cell destruction after engraftment into HLA-A2 transgenic NOD/scid/IL2RG null mice.

by Wendy W J Unger, Todd Pearson, Joana R F Abreu, Sandra Laban, Arno R van der Slik, Sacha Mulder-van der Kracht, Michel G D Kester, Dave V Serreze, Leonard D Shultz, Marieke Griffioen, Jan Wouter Drijfhout, Dale L Greiner, Bart O Roep
Published 2012-01-01

Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97.

by Hanneke Hoelen, Arnaud Zaldumbide, Wouter F van Leeuwen, Ellen C W Torfs, Marten A Engelse, Chopie Hassan, Robert Jan Lebbink, Eelco J de Koning, Maaike E Resssing, Arnoud H de Ru, Peter A van Veelen, Rob C Hoeben, Bart O Roep, Emmanuel J H J Wiertz
Published 2015-01-01

Distinct fecal and oral microbiota composition in human type 1 diabetes, an observational study.

by Pieter F de Groot, Clara Belzer, Ömrüm Aydin, Evgeni Levin, Johannes H Levels, Steven Aalvink, Fransje Boot, Frits Holleman, Daniël H van Raalte, Torsten P Scheithauer, Suat Simsek, Frank G Schaap, Steven W M Olde Damink, Bart O Roep, Joost B Hoekstra, Willem M de Vos, Max Nieuwdorp
Published 2017-01-01

Cellular islet autoimmunity associates with clinical outcome of islet cell transplantation.

by Volkert A L Huurman, Robert Hilbrands, Gabriëlle G M Pinkse, Pieter Gillard, Gaby Duinkerken, Pieter van de Linde, Petronella M W van der Meer-Prins, Minke F J Versteeg-van der Voort Maarschalk, Koen Verbeeck, Behrooz Z Alizadeh, Chantal Mathieu, Frans K Gorus, Dave L Roelen, Frans H J Claas, Bart Keymeulen, Daniel G Pipeleers, Bart O Roep
Published 2008-06-01