Administration, Buccal Administration, Intranasal Administration, Intravenous Administration, Sublingual Adolescent Adult Analgesics, Opioid Article Drug Overdose Female Humans Injections, Intramuscular Male Middle Aged Naloxone Narcan Narcotic Antagonists Opioid Opioid use disorder Overdose Pain Patient Preference Young Adult adolescent adult analgesia buccal drug administration cohort analysis controlled study crowdsourcing