The diterpenoid 7-keto-sempervirol, derived from Lycium chinense, displays anthelmintic activity against both Schistosoma mansoni and Fasciola hepatica.

by Jennifer Edwards, Martha Brown, Emily Peak, Barbara Bartholomew, Robert J Nash, Karl F Hoffmann
Published 2015-03-01

Iminosugar idoBR1 Isolated from Cucumber Cucumis sativus Reduces Inflammatory Activity

by Robert J. Nash, Barbara Bartholomew, Yana B. Penkova, Dino Rotondo, Fernanda Yamasaka, Graham P. Stafford, Sarah F. Jenkinson, George W. J. Fleet
Published 2020-06-01

An Abies procera-derived tetracyclic triterpene containing a steroid-like nucleus core and a lactone side chain attenuates in vitro survival of both Fasciola hepatica and Schistoso...

by Helen L. Whiteland, Anand Chakroborty, Josephine E. Forde-Thomas, Alessandra Crusco, Alan Cookson, Jackie Hollinshead, Caroline A. Fenn, Barbara Bartholomew, Peter A. Holdsworth, Maggie Fisher, Robert J. Nash, Karl F. Hoffmann
Published 2018-12-01

Temperate Zone Plant Natural Products—A Novel Resource for Activity against Tropical Parasitic Diseases

by Hamza Hameed, Elizabeth F. B. King, Katerina Doleckova, Barbara Bartholomew, Jackie Hollinshead, Haddijatou Mbye, Imran Ullah, Karen Walker, Maria Van Veelen, Somaia Saif Abou-Akkada, Robert J. Nash, Paul D. Horrocks, Helen P. Price
Published 2021-03-01