PTEN: Tumor Suppressor and Metabolic Regulator

by Chien-Yu Chen, Jingyu Chen, Lina He, Bangyan L. Stiles, Bangyan L. Stiles
Published 2018-07-01

Brain metabolic and functional alterations in a liver-specific PTEN knockout mouse model.

by Ishan Patil, Harsh Sancheti, Bangyan L Stiles, Enrique Cadenas
Published 2018-01-01

Emerging signals regulating liver tumor initiating cells

by Jingyu Chen, Chien-Yu Chen, Christopher Nguyen, Lulu Chen, Kangmin Lee, Bangyan L. Stiles
Published 2018-06-01

Transformation of SOX9+ cells by Pten deletion synergizes with steatotic liver injury to drive development of hepatocellular and cholangiocarcinoma

by Jingyu Chen, Anketse Debebe, Ni Zeng, Janel Kopp, Lina He, Maike Sander, Bangyan L. Stiles
Published 2021-06-01

High-fat diet induces hepatic insulin resistance and impairment of synaptic plasticity.

by Zhigang Liu, Ishan Y Patil, Tianyi Jiang, Harsh Sancheti, John P Walsh, Bangyan L Stiles, Fei Yin, Enrique Cadenas
Published 2015-01-01

Maf1 is a novel target of PTEN and PI3K signaling that negatively regulates oncogenesis and lipid metabolism.

by Beth M Palian, Aarti D Rohira, Sandra A S Johnson, Lina He, Ni Zheng, Louis Dubeau, Bangyan L Stiles, Deborah L Johnson
Published 2014-12-01

Short term feeding of a high fat diet exerts an additive effect on hepatocellular damage and steatosis in liver-specific PTEN knockout mice.

by Colin T Shearn, Kelly E Mercer, David J Orlicky, Leah Hennings, Rebecca L Smathers-McCullough, Bangyan L Stiles, Martin J J Ronis, Dennis R Petersen
Published 2014-01-01

Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage.

by Colin T Shearn, David J Orlicky, Rebecca L McCullough, Hua Jiang, Kenneth N Maclean, Kelly E Mercer, Bangyan L Stiles, Laura M Saba, Martin J Ronis, Dennis R Petersen
Published 2016-01-01