Broadly Protective Strategies Against Influenza Viruses: Universal Vaccines and Therapeutics

by Olivia A. Vogel, Balaji Manicassamy
Published 2020-02-01

Influenza A virus infection impacts systemic microbiota dynamics and causes quantitative enteric dysbiosis

by Soner Yildiz, Béryl Mazel-Sanchez, Matheswaran Kandasamy, Balaji Manicassamy, Mirco Schmolke
Published 2018-01-01

The p150 Isoform of ADAR1 Blocks Sustained RLR signaling and Apoptosis during Influenza Virus Infection.

by Olivia A Vogel, Julianna Han, Chieh-Yu Liang, Santhakumar Manicassamy, Jasmine T Perez, Balaji Manicassamy
Published 2020-09-01

RIG-I Signaling Is Critical for Efficient Polyfunctional T Cell Responses during Influenza Virus Infection.

by Matheswaran Kandasamy, Amol Suryawanshi, Smanla Tundup, Jasmine T Perez, Mirco Schmolke, Santhakumar Manicassamy, Balaji Manicassamy
Published 2016-07-01

Endothelial cell tropism is a determinant of H5N1 pathogenesis in mammalian species.

by Smanla Tundup, Matheswaran Kandasamy, Jasmine T Perez, Nacho Mena, John Steel, Tamas Nagy, Randy A Albrecht, Balaji Manicassamy
Published 2017-03-01

Influenza-infected neutrophils within the infected lungs act as antigen presenting cells for anti-viral CD8(+) T cells.

by Matthew M Hufford, Graham Richardson, Haixia Zhou, Balaji Manicassamy, Adolfo García-Sastre, Richard I Enelow, Thomas J Braciale
Published 2012-01-01

A Simple and Robust Approach for Evaluation of Antivirals Using a Recombinant Influenza Virus Expressing Gaussia Luciferase

by Ping Li, Qinghua Cui, Lin Wang, Xiujuan Zhao, Yingying Zhang, Balaji Manicassamy, Yong Yang, Lijun Rong, Ruikun Du
Published 2018-06-01

Genome-wide CRISPR/Cas9 Screen Identifies Host Factors Essential for Influenza Virus Replication

by Julianna Han, Jasmine T. Perez, Cindy Chen, Yan Li, Asiel Benitez, Matheswaran Kandasamy, Yoontae Lee, Jorge Andrade, Benjamin tenOever, Balaji Manicassamy
Published 2018-04-01

Protection of mice against lethal challenge with 2009 H1N1 influenza A virus by 1918-like and classical swine H1N1 based vaccines.

by Balaji Manicassamy, Rafael A Medina, Rong Hai, Tshidi Tsibane, Silke Stertz, Estanislao Nistal-Villán, Peter Palese, Christopher F Basler, Adolfo García-Sastre
Published 2010-01-01

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species.

by Mirco Schmolke, Balaji Manicassamy, Lindomar Pena, Troy Sutton, Rong Hai, Zsuzsanna T Varga, Benjamin G Hale, John Steel, Daniel R Pérez, Adolfo García-Sastre
Published 2011-08-01

Variations in the hemagglutinin of the 2009 H1N1 pandemic virus: potential for strains with altered virulence phenotype?

by Jianqiang Ye, Erin M Sorrell, Yibin Cai, Hongxia Shao, Kemin Xu, Lindomar Pena, Danielle Hickman, Haichen Song, Matthew Angel, Rafael A Medina, Balaji Manicassamy, Adolfo Garcia-Sastre, Daniel R Perez
Published 2010-10-01

Host factor Rab11a is critical for efficient assembly of influenza A virus genomic segments.

by Julianna Han, Ketaki Ganti, Veeresh Kumar Sali, Carly Twigg, Yifeng Zhang, Senthamizharasi Manivasagam, Chieh-Yu Liang, Olivia A Vogel, Iris Huang, Shanan N Emmanuel, Jesse Plung, Lillianna Radoshevich, Jasmine T Perez, Anice C Lowen, Balaji Manicassamy
Published 2021-05-01

Host modulators of H1N1 cytopathogenicity.

by Samuel E Ward, Hyun Seok Kim, Kakajan Komurov, Saurabh Mendiratta, Pei-Ling Tsai, Mirco Schmolke, Neal Satterly, Balaji Manicassamy, Christian V Forst, Michael G Roth, Adolfo García-Sastre, Katarzyna M Blazewska, Charles E McKenna, Beatriz M Fontoura, Michael A White
Published 2012-01-01