Methods for Identification of Substrates/Inhibitors of FCP/SCP Type Protein Ser/Thr Phosphatases

by Masataka Mizunuma, Atsushi Kaneko, Shunta Imai, Kazuhiro Furukawa, Yoshiro Chuman
Published 2020-12-01

Preventive Effect of TU-100 on a Type-2 Model of Colitis in Mice: Possible Involvement of Enhancing Adrenomedullin in Intestinal Epithelial Cells

by Atsushi Kaneko, Toru Kono, Naoko Miura, Naoko Tsuchiya, Masahiro Yamamoto
Published 2013-01-01

Development of Specific Inhibitors for Oncogenic Phosphatase PPM1D by Using Ion-Responsive DNA Aptamer Library

by Atsushi Kaneko, Miyuu Watari, Masataka Mizunuma, Hikaru Saito, Kazuhiro Furukawa, Yoshiro Chuman
Published 2020-10-01

Inhibition of Human Kallikrein 5 Protease by Triterpenoids from Natural Sources

by Yosuke Matsubara, Takashi Matsumoto, Junichi Koseki, Atsushi Kaneko, Setsuya Aiba, Kenshi Yamasaki
Published 2017-10-01

Pharmacokinetic Study of Bioactive Flavonoids in the Traditional Japanese Medicine Keigairengyoto Exerting Antibacterial Effects against Staphylococcus aureus

by Takashi Matsumoto, Atsushi Kaneko, Junichi Koseki, Yosuke Matsubara, Setsuya Aiba, Kenshi Yamasaki
Published 2018-01-01

Identification of a Specific Inhibitor of Human Scp1 Phosphatase Using the Phosphorylation Mimic Phage Display Method

by Takuya Yoshida, Kazuki Yamazaki, Shunta Imai, Akinori Banno, Atsushi Kaneko, Kazuhiro Furukawa, Yoshiro Chuman
Published 2019-10-01

Oral Administration of the Japanese Traditional Medicine Keishibukuryogan-ka-yokuinin Decreases Reactive Oxygen Metabolites in Rat Plasma: Identification of Chemical Constituents C...

by Yosuke Matsubara, Takashi Matsumoto, Kyoji Sekiguchi, Junichi Koseki, Atsushi Kaneko, Takuji Yamaguchi, Yumiko Kurihara, Hiroyuki Kobayashi
Published 2017-02-01

Wogonin Attenuates Ovalbumin Antigen-Induced Neutrophilic Airway Inflammation by Inhibiting Th17 Differentiation

by Rie Takagi, Masaaki Kawano, Kazuyuki Nakagome, Kumiko Hashimoto, Takehiro Higashi, Katsuya Ohbuchi, Atsushi Kaneko, Sho Matsushita
Published 2014-01-01

Increase of <i>Akkermansia muciniphila</i> by a Diet Containing Japanese Traditional Medicine Bofutsushosan in a Mouse Model of Non-Alcoholic Fatty Liver Disease

by Mitsue Nishiyama, Nobuhiro Ohtake, Atsushi Kaneko, Naoko Tsuchiya, Sachiko Imamura, Seiichi Iizuka, Shiori Ishizawa, Akinori Nishi, Masahiro Yamamoto, Akinobu Taketomi, Toru Kono
Published 2020-03-01

Suppression of Propionibacterium acnes-Induced Dermatitis by a Traditional Japanese Medicine, Jumihaidokuto, Modifying Macrophage Functions

by Kyoji Sekiguchi, Junichi Koseki, Kazuaki Tsuchiya, Yosuke Matsubara, Seiichi Iizuka, Sachiko Imamura, Takashi Matsumoto, Junko Watanabe, Atsushi Kaneko, Setsuya Aiba, Kenshi Yamasaki
Published 2015-01-01

Plasma Pharmacokinetics of Polyphenols in a Traditional Japanese Medicine, Jumihaidokuto, Which Suppresses Propionibacterium acnes-Induced Dermatitis in Rats

by Takashi Matsumoto, Yousuke Matsubara, Yasuharu Mizuhara, Kyoji Sekiguchi, Junichi Koseki, Kazuaki Tsuchiya, Hiroaki Nishimura, Junko Watanabe, Atsushi Kaneko, Kazuya Maemura, Tomohisa Hattori, Yoshio Kase
Published 2015-09-01

Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus acutissima Cortex

by Junichi Koseki, Takashi Matsumoto, Yosuke Matsubara, Kazuaki Tsuchiya, Yasuharu Mizuhara, Kyoji Sekiguchi, Hiroaki Nishimura, Junko Watanabe, Atsushi Kaneko, Tomohisa Hattori, Kazuya Maemura, Yoshio Kase
Published 2015-01-01

TU-100 (Daikenchuto) and ginger ameliorate anti-CD3 antibody induced T cell-mediated murine enteritis: microbe-independent effects involving Akt and NF-κB suppression.

by Nobuhiro Ueno, Takumu Hasebe, Atsushi Kaneko, Masahiro Yamamoto, Mikihiro Fujiya, Yutaka Kohgo, Toru Kono, Chong-Zhi Wang, Chun-Su Yuan, Marc Bissonnette, Eugene B Chang, Mark W Musch
Published 2014-01-01

Predictors for clinical effectiveness of baricitinib in rheumatoid arthritis patients in routine clinical practice: data from a Japanese multicenter registry

by Nobunori Takahashi, Shuji Asai, Tomonori Kobayakawa, Atsushi Kaneko, Tatsuo Watanabe, Takefumi Kato, Tsuyoshi Nishiume, Hisato Ishikawa, Yutaka Yoshioka, Yasuhide Kanayama, Tsuyoshi Watanabe, Yuji Hirano, Masahiro Hanabayashi, Yuichiro Yabe, Yutaka Yokota, Mochihito Suzuki, Yasumori Sobue, Kenya Terabe, Naoki Ishiguro, Toshihisa Kojima
Published 2020-12-01