In Silico Design and Selection of New Tetrahydroisoquinoline-Based CD44 Antagonist Candidates

by Angel J. Ruiz-Moreno, Atilio Reyes-Romero, Alexander Dömling, Marco A. Velasco-Velázquez
Published 2021-03-01

Production of “biobetter” variants of glucarpidase with enhanced enzyme activity

by Alanod D. Al-Qahtani, Sara S. Bashraheel, Fatma B. Rashidi, C. David O’Connor, Atilio Reyes Romero, Alexander Domling, Sayed K. Goda
Published 2019-04-01

A fragment-based approach identifies an allosteric pocket that impacts malate dehydrogenase activity

by Atilio Reyes Romero, Serjey Lunev, Grzegorz M. Popowicz, Vito Calderone, Matteo Gentili, Michael Sattler, Jacek Plewka, Michał Taube, Maciej Kozak, Tad A. Holak, Alexander S. S. Dömling, Matthew R. Groves
Published 2021-08-01

STXBP6, reciprocally regulated with autophagy, reduces triple negative breast cancer aggressiveness

by Govinda Lenka, Jingxuan Shan, Najeeb Halabi, Sirin W J Abuaqel, Neha Goswami, Frank Schmidt, Shaza Zaghlool, Atilio Reyes Romero, Murugan Subramanian, Salha Boujassoum, Issam Al‐Bozom, Salah Gehani, Noor Al Khori, Davide Bedognetti, Karsten Suhre, Xiaojing Ma, Alexander Dömling, Arash Rafii, Lotfi Chouchane
Published 2020-07-01