Determining the binding affinity of therapeutic monoclonal antibodies towards their native unpurified antigens in human serum.

by Christine Bee, Yasmina N Abdiche, Jaume Pons, Arvind Rajpal
Published 2013-01-01

Exploring the dynamic range of the kinetic exclusion assay in characterizing antigen-antibody interactions.

by Christine Bee, Yasmina N Abdiche, Donna M Stone, Sierra Collier, Kevin C Lindquist, Alanna C Pinkerton, Jaume Pons, Arvind Rajpal
Published 2012-01-01

High-throughput epitope binning assays on label-free array-based biosensors can yield exquisite epitope discrimination that facilitates the selection of monoclonal antibodies with...

by Yasmina Noubia Abdiche, Adam Miles, Josh Eckman, Davide Foletti, Thomas J Van Blarcom, Yik Andy Yeung, Jaume Pons, Arvind Rajpal
Published 2014-01-01

Structures of mouse and human GITR–GITRL complexes reveal unique TNF superfamily interactions

by Feng Wang, Bryant Chau, Sean M. West, Christopher R. Kimberlin, Fei Cao, Flavio Schwarz, Barbara Aguilar, Minhua Han, Winse Morishige, Christine Bee, Gavin Dollinger, Arvind Rajpal, Pavel Strop
Published 2021-03-01

Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire

by Yik Andy Yeung, Davide Foletti, Xiaodi Deng, Yasmina Abdiche, Pavel Strop, Jacob Glanville, Steven Pitts, Kevin Lindquist, Purnima D. Sundar, Marina Sirota, Adela Hasa-Moreno, Amber Pham, Jody Melton Witt, Irene Ni, Jaume Pons, David Shelton, Arvind Rajpal, Javier Chaparro-Riggers
Published 2016-11-01

Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy.

by Magdalena Dorywalska, Pavel Strop, Jody A Melton-Witt, Adela Hasa-Moreno, Santiago E Farias, Meritxell Galindo Casas, Kathy Delaria, Victor Lui, Kris Poulsen, Janette Sutton, Gary Bolton, Dahui Zhou, Ludivine Moine, Russell Dushin, Thomas-Toan Tran, Shu-Hui Liu, Mathias Rickert, Davide Foletti, David L Shelton, Jaume Pons, Arvind Rajpal
Published 2015-01-01