Evidence for Anti-Viral Effects of Complete Freund’s Adjuvant in the Mouse Model of Enterovirus Infection

by Arunakumar Gangaplara, Chandirasegaran Massilamany, Ninaad Lasrado, David Steffen, Jay Reddy
Published 2020-07-01

Identification of Immunogenic Epitopes That Permit the Detection of Antigen-Specific T Cell Responses in Multiple Serotypes of Group B Coxsackievirus Infections

by Ninaad Lasrado, Arunakumar Gangaplara, Rajkumar Arumugam, Chandirasegaran Massilamany, Sayli Pokal, Yuzhen Zhou, Shi-Hua Xiang, David Steffen, Jay Reddy
Published 2020-03-01

Direct staining with major histocompatibility complex class II dextramers permits detection of antigen-specific, autoreactive CD4 T cells in situ.

by Chandirasegaran Massilamany, Arunakumar Gangaplara, Ting Jia, Christian Elowsky, Guobin Kang, Jean-Jack Riethoven, Qingsheng Li, You Zhou, Jay Reddy
Published 2014-01-01

Mutations in the 5' NTR and the Non-Structural Protein 3A of the Coxsackievirus B3 Selectively Attenuate Myocarditogenicity.

by Chandirasegaran Massilamany, Arunakumar Gangaplara, Rakesh H Basavalingappa, Rajkumar A Rajasekaran, Hiep Vu, Jean-Jack Riethoven, David Steffen, Asit K Pattnaik, Jay Reddy
Published 2015-01-01

Correction: Mutations in the 5' NTR and the Non-Structural Protein 3A of the Coxsackievirus B3 Selectively Attenuate Myocarditogenicity.

by Chandirasegaran Massilamany, Arunakumar Gangaplara, Rakesh H Basavalingappa, Rajkumar A Rajasekaran, Hiep Vu, Jean-Jack Riethoven, David Steffen, Asit K Pattnaik, Jay Reddy
Published 2015-01-01

CD47 Expression in Natural Killer Cells Regulates Homeostasis and Modulates Immune Response to Lymphocytic Choriomeningitis Virus

by Pulak Ranjan Nath, Arunakumar Gangaplara, Dipasmita Pal-Nath, Ajeet Mandal, Dragan Maric, John M. Sipes, Maggie Cam, Ethan M. Shevach, David D. Roberts
Published 2018-12-01

SJL mice infected with Acanthamoeba castellanii develop central nervous system autoimmunity through the generation of cross-reactive T cells for myelin antigens.

by Chandirasegaran Massilamany, Francine Marciano-Cabral, Bruno da Rocha-Azevedo, Melissa Jamerson, Arunakumar Gangaplara, David Steffen, Rana Zabad, Zsolt Illes, Raymond A Sobel, Jay Reddy
Published 2014-01-01

β1-Adrenergic Receptor Contains Multiple IAk and IEk Binding Epitopes That Induce T Cell Responses with Varying Degrees of Autoimmune Myocarditis in A/J Mice

by Rakesh H. Basavalingappa, Chandirasegaran Massilamany, Bharathi Krishnan, Arunakumar Gangaplara, Rajkumar A. Rajasekaran, Muhammad Z. Afzal, Jean-Jack Riethoven, Jennifer L. Strande, David Steffen, Jay Reddy
Published 2017-11-01

Type I interferon signaling attenuates regulatory T cell function in viral infection and in the tumor microenvironment.

by Arunakumar Gangaplara, Craig Martens, Eric Dahlstrom, Amina Metidji, Ameya S Gokhale, Deborah D Glass, Maria Lopez-Ocasio, Rachel Baur, Kishore Kanakabandi, Stephen F Porcella, Ethan M Shevach
Published 2018-04-01

Attenuated strain of CVB3 with a mutation in the CAR-interacting region protects against both myocarditis and pancreatitis

by Ninaad Lasrado, Arunakumar Gangaplara, Chandirasegaran Massilamany, Rajkumar Arumugam, Allison Shelbourn, Mahima T. Rasquinha, Rakesh H. Basavalingappa, Gustavo Delhon, Shi-Hua Xiang, Asit K. Pattnaik, David Steffen, Jay Reddy
Published 2021-06-01